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Meg Mangin R.N.
Research Team (on leave)
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Posted: Sat Sep 10th, 2005 01:16 |
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Can I donate blood, organs, tissue or bone marrow if I have a Th1 inflammatory disease?
Organs and tissue (Kveim test) from sarcoidosis patients have caused sarcoidosis in the transplanted recipients. This is proof that the bacterial pathogens can be transferred and trigger the same abnormal immune system response in susceptible people.
Sarcoidosis patients are not allowed to give blood by the USA Red Cross. They are allowed to give organ transplants, and Dr Moller noted that during transplants involving patients with sarcoidosis, patients who receive a donor organ from a sarcoidosis patients develop the disease, and clean organs transplanted into sarc patients become infected.(see full text of this paper: http://tinyurl.com/6xx46 )
Blood banks may not have strict regulations against donations from people with so-called autoimmune diseases or Th1 inflammation but now that we know the bacterial etiology, we advise people not to donate blood, bone marrow, organs or other tissues.
TRANSPLANT talk: Jillbc and the Fisherman
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"One of Lida Mattman's slides in Chicago shows L-forms in supposedly sterile, whole Red-Cross blood.L-forms seem to survive all attempts at sterilization.
Lida is certain that transfusion is one of the reasons that the chronic diseases have balloned to epidemic proportions over the last 50 years. Remember, the Red Cross blood transfusion service grew at the end of the second world war, and was not around during the first half of this century. Neither were beta-lactam antibiotics, Vitamin D supplementation, the Sun-worshipping ethos, and other factors which, IMO, have all contributed to the Th1 autoimmune diseases spiralling out of control."
..Trevor..
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This letter in CHEST online advocates the removal of phagocytic cells from blood being transfused. Now the big question is - what could those phagocytes possibly have in them that might promote infection? LOLOL
"Leukoreduction of transfusions and blood stream infections"
http://www.chestjournal.org/cgi/eletters/127/5/1722
..Trevor..
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This report indicates sarcoidosis occurs following stem cell transplants:
Pulmonary sarcoidosis following stem cell transplantation: is it more than a chance occurrence?
Chest. 2004 Aug;126(2):642-4.
PMID: 15302757 [PubMed - indexed for MEDLINE]
http://tinyurl.com/6q7vb
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Tick-Borne Disease Transmission by Blood Donation Prevalent in Endemic Areas
Mary Beth Nierengarten
Medscape Medical News 2005. © 2005 Medscape
http://www.medscape.com/viewarticle/514364?src=mp
"Ms. Nguyen emphasized that "anybody who has had B microti is permanently prohibited from donating blood" and is registered in the blood bank system of the Red Cross nationwide. **However, it is important to identify those people infected with B microti prior to blood donation.** According to Ms. Nguyen, most of the transfusion-related transmission occurs through people who are infected with the tick-borne disease but who are asymptomatic".
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Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
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Belinda
Research Team
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Posted: Mon Sep 4th, 2006 02:50 |
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Sarcoidosis has been transmitted to organ recipients from organ donors.
Padilla ML, Schilero GJ, Teirstein AS.
Donor-acquired sarcoidosis.
Sarcoidosis Vasc Diffuse Lung Dis 2002;19:18-24.
Lancet published this case report in 1990 of sarcoidosis after a heart transplant:
Burke W, Keogh A, Maloney P, Delprado W, Bryant D, Spratt P.
Transmission of sarcoidosis via cardiac transplantation.
Lancet Dec 22-29 1990; 336(8730):1579. PMID: 1979389
Sarcoidosis has been reported to have been transmitted in bone marrow and stem cells.
Heyll A, Meckenstock G, Aul C, Söhngen D, Borchard F, Hadding U, Mödder U, et al.
Possible transmission of sarcoidosis via allogeneic bone marrow transplantation.
Bone Marrow Transplant 1994; 14:161-164.
Granulomatous pneumonitis following bone marrow transplantation.
Bone Marrow Transplant. 2001 Sep;28(6):627-30.
PMID: 11607780 [PubMed - indexed for MEDLINE]
Pulmonary sarcoidosis following stem cell transplantation: is it more than a chance occurrence?
Chest. 2004 Aug;126(2):642-4.
PMID: 15302757 [PubMed - indexed for MEDLINE]
There have been reports of sarcoidosis lesions at venipuncture sites (sort of the way sarcoidosis erupts in scars and tatoos).
Cutaneous sarcoidosis in venepuncture sites.
Br Med J. 1973 Mar 3;1(5852):547. No abstract available.
PMID: 4692686 [PubMed - indexed for MEDLINE
Hancock BW. Cutaneous sarcoidosis in blood donation venepuncture sites.
Br Med J. 1972 Dec 23;4(842):706-8. No abstract available.
PMID: 4646848 [PubMed - indexed for MEDLINE]
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Belinda
Research Team
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Posted: Mon Sep 4th, 2006 03:02 |
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(filelink)
FDA Restricts Distribution of Blood Collected from People with Sarcoidosis
The FDA has a history of enforcing its restriction on the distribution of blood from sarcoidosis patients. You can see on the FDA website and this FDA enforcement report that in 1997 the FDA took action against the American Red Cross because blood was collected from a donor/donors who had been diagnosed with sarcoidois.
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