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Bacterial Iron Acquisition Systems
 Moderated by: Dr Trevor Marshall  

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Lottis
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Joined: Sun Jan 21st, 2007
Location: Sweden
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 Posted: Sun Jan 25th, 2009 11:43

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Amy is really doing some groundbreaking work! I am eagerly waiting for the paper to come out. :) That is going to be very interesting!

:? Back now to the iron.
http://www.jimmunol.org/cgi/reprint/178/10/6367

On page 3, at the right column in the journal of immunology, read the section that starts with this sentence;

LF levels in PMA-treated PMN supernatants from normal controls
and CGD patients were determined by ELISA.


There is a dysfunction of the ability to disable the pathogens by requesting their iron, in the CGD patients.



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Dr Trevor Marshall
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 Posted: Sun Jan 25th, 2009 13:03

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Lottis,
You are trying to read too much into these in-vitro experiments, which at best are only a poor simulation of what happens in the diseased body.

It is well known that  many bacterial strains accrete ferritin. No need to focus on  fungus.
 

Lottis
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 Posted: Sun Jan 25th, 2009 13:22

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Sorry, :? I am not focus on fungus....that was a side topic.It is the neutrophiles function that caught my interest.

 I know that pathogens rob us from our iron. That is why I do not want to give iron to my daughter, who has been diagnosed by a hematologist of being low in iron. This doctor suggested iron supplementation, I  hesitated, because I knew this.

I am trying to find another solution for my daughter and her sick and tiredness.
http://curemyth1.org/view_topic.php?id=1072&forum_id=5&highlight=Little+My

No doctor wants to even discuss the MP treatment for her.
She is also low in her neutrophile counts, so I see a slight connection here. Her B12 is around 400, and I have no clue if B12 supplementation would be good for her.

She is in her final year at school, and she is aiming for high grades. That is why I need to understand this subject, you see. ;) -She has to get some help.

/Lottis



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HTN,LVH,CHF,arrhythmia,hypercholesterol,IBS? fibromyalgia?salivarystones,gallstones,ect...|15feb-07 init. 1,25D 37,5,|25-D 7,8(latest 15/2-07)| Ph1 29/7-08| Palliativ Meds. at the present; |Zoloft|NoIR's|covered up|disabled|
Lottis
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 Posted: Wed Feb 4th, 2009 10:06

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Curcumin in curry, might effect the levels of iron.

http://bloodjournal.hematologylibrary.org/cgi/content/abstract/113/2/462



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HTN,LVH,CHF,arrhythmia,hypercholesterol,IBS? fibromyalgia?salivarystones,gallstones,ect...|15feb-07 init. 1,25D 37,5,|25-D 7,8(latest 15/2-07)| Ph1 29/7-08| Palliativ Meds. at the present; |Zoloft|NoIR's|covered up|disabled|
MarkN
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Joined: Sun Nov 5th, 2006
Location: Charlotte, North Carolina USA
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 Posted: Wed Feb 4th, 2009 20:19

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When I was researching lactoferrin, yes it keeps iron from the bacteria ... some say it also has a direct antibacterial effect, and I even found some references that it may send a chemical "message" that tells the bugs not to form biofilm.

So I don't know what it "really" does, except that it gives me very strong IP, especially where I need it, in the brain. It is also said to "modulate the immune system", which is generally a bad idea, so I don't take it very often. I do feel an anti-inflammatory effect for about 12 hours after taking it.



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General insanity (Aspergers ??), CFS, some joint paint ...
11/06:1,25D=37 25D=43, 3/08:25D<7 ... Avoid D 12/06 ... PhaseOne 1/07, PhaseTwo 3/07, PhaseThree 9/07
cschifel
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Joined: Thu Dec 13th, 2007
Location: Toronto, Ontario Canada
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 Posted: Thu Mar 19th, 2009 19:52

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I have been using the tinted Kabana sunscreen. It is tinted with iron. Should I stop? I use it when I have to go out in the sun or heavy flourescent lighting. I don't now how much iron can be absorbed through the skin. I only put it on my face.

Carmen


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