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MP in the news - Vitamin D debate continues
 Moderated by: Dr Trevor Marshall  

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Deedee
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Joined: Sun Dec 28th, 2008
Location: Asheville, North Carolina USA
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 Posted: Mon Feb 8th, 2010 05:00

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Along with Amy's 14 Myths about Vitamin D, I was able to use your article on Facebook to counter-act a friend's post from Dr. Weil promoting Vitamin D. Here is his article:
http://www.huffingtonpost.com/andrew-weil-md/new-recommendation-why-yo_b_446580.html

Frightening.



____________________
Sarc in lymph nodes. D14. Back to Phase I, 100 mino Benicar 4X/day. Lipids high. 7/07 check-up: Normal PFTs/CXR improved; Quecentin/guaifensin if lymph nodes hurt. Spleen pains. Began MP 8/08
Bane
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 Posted: Mon Feb 8th, 2010 15:49

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The Effects of Vitamin D Supplementation on Physical Function and Quality of Life in Older Heart Failure Patients: A Randomised Controlled Trial.

http://www.ncbi.nlm.nih.gov/pubmed/20103775

Cholecalciferol Supplementation throughout Winter Does Not Affect Markers of Bone Turnover in Healthy Young and Elderly Adults.

http://www.ncbi.nlm.nih.gov/pubmed/20089776

Once-weekly dose of 8400 IU vitamin D3 compared with placebo: effects on neuromuscular function and tolerability in older adults with vitamin D insufficiency.

http://www.ncbi.nlm.nih.gov/pubmed/20130093

A Pilot Study of Vitamin D and Balance Characteristics in Middle-Aged, Healthy Individuals.

http://www.ncbi.nlm.nih.gov/pubmed/20129509



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Oral Lichen Planus(mild)/Clubbed Finger (digital clubbing)Last 25D 5.6ng/ml, phase3
Bane
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 Posted: Mon Feb 8th, 2010 16:26

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What Is All This Commotion about Vitamin D?

http://www.nature.com/jid/journal/v130/n2/full/jid2009353a.html

Patient level pooled analysis of 68 500 patients from seven major vitamin D fracture trials in US and Europe.

http://www.ncbi.nlm.nih.gov/pubmed/20068257

Plasma 25-hydroxyvitamin D and prostate cancer risk: The Multiethnic Cohort.

http://www.ncbi.nlm.nih.gov/pubmed/20064705

"When clinically defined cutpoints were used, there was no increased risk for the lowest 25(OH)D concentration (OR for <20 versus 30-<50ng/ml=1.10, 95% CI=0.68-1.78), while there was a suggestive increased risk for higher concentrations (OR for 50ng/ml=1.52, 95% CI=0.92-2.51)."

Hormone therapy in rheumatic diseases.

http://www.ncbi.nlm.nih.gov/pubmed/20075732

Last edited on Mon Feb 8th, 2010 16:37 by Bane



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Oral Lichen Planus(mild)/Clubbed Finger (digital clubbing)Last 25D 5.6ng/ml, phase3
Rico
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 Posted: Tue Feb 9th, 2010 00:15

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Good finds, Bane!



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No diagnosis/some symptoms; wife with Sarc on MP; Olm 40mg q6h| avoid D| 1,25D=63 25D=32 (May 2006) 1,25D=44; 25D=10(Dec 2006)PhaseI(May06) PhaseII(Aug06) PhaseIII(Aug07)
Bane
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 Posted: Wed Feb 10th, 2010 14:55

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No improvement in cardiovascular risk factors in overweight and obese subjects after supplementation with vitamin D for 1 year.

http://www.ncbi.nlm.nih.gov/pubmed/20141565

Vitamin D metabolism.

http://www.ncbi.nlm.nih.gov/pubmed/20136904

"More recently, it has been found that calcitriol or vitamin D analogs have photoprotective effects and can reduce UV-induced deoxyribonucleic acid damage."

Protection from unwise sun exposure, and not for storage?

 



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Oral Lichen Planus(mild)/Clubbed Finger (digital clubbing)Last 25D 5.6ng/ml, phase3
leroybrown
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 Posted: Tue Feb 16th, 2010 16:04

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The latest horrendous article: http://www.cbc.ca/canada/ottawa/story/2010/02/12/ottawa-immigrants-vitamin-d.html?ref=rss

"immigration to Canada could be dangerous or bad for your health"



____________________
Autoimmune Pure Red Cell Aplasia, Jan 2009, Agranulocytosis 1991
Jan 14: hgb: 84, wbc 1.1
25D = 25 1,25D = 58 Aug 18/09
Phase 1: Sept 29/09 benicar 40mg q8hrs * Nov 26/09 40mg q6hrs
Deedee
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 Posted: Tue Feb 16th, 2010 17:20

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'If your shadow is longer than your height, it's not even worth being outside naked on a sunny day.' Even funnier is picturing the guy who said it "naked outside on a sunny day" studying his shadow.

LOL....LOL....LOL
Thanks for the belly-laugh, I needed that!



____________________
Sarc in lymph nodes. D14. Back to Phase I, 100 mino Benicar 4X/day. Lipids high. 7/07 check-up: Normal PFTs/CXR improved; Quecentin/guaifensin if lymph nodes hurt. Spleen pains. Began MP 8/08
leroybrown
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 Posted: Tue Feb 16th, 2010 17:27

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What must the neighbours think!



____________________
Autoimmune Pure Red Cell Aplasia, Jan 2009, Agranulocytosis 1991
Jan 14: hgb: 84, wbc 1.1
25D = 25 1,25D = 58 Aug 18/09
Phase 1: Sept 29/09 benicar 40mg q8hrs * Nov 26/09 40mg q6hrs
Bane
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 Posted: Tue Feb 16th, 2010 18:48

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Vitamin D and endocrine diseases

http://www.ncbi.nlm.nih.gov/pubmed/19768253

" In obese individuals, the impaired vitamin D endocrine system, characterized by high levels of PTH and 1,25(OH)(2)D(3) could induce a negative feedback for the hepatic synthesis of 25(OH)D and also contribute to a higher intracellular calcium, which in turn secrete less insulin and deteriorate insulin sensitivity. In hypertension, vitamin D could act on renin-angiotensin system and also in vascular function."



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Oral Lichen Planus(mild)/Clubbed Finger (digital clubbing)Last 25D 5.6ng/ml, phase3
marysue
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 Posted: Thu Feb 18th, 2010 04:47

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Thanks, Bane, for all the links....interesting reading.

Deedee and Deb (leroy)--too funny!!!! Thanks for the laughs. Many years ago I was stationed in Iceland and saw lots of looooooong shadows...but they were all fully clothed in furry parkas!

Marysue



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Thanks Dr. Marshall and staff for all the support!
CFS/FM '95; infert/endomet '02; hypotension; cardiac IP; start light restrict. Oct08; 125D=70 25D=30 (Feb09); Benicar26Apr09; NoIRs, low light, no sun; 25D=10 (Jun09); 25D=5 (Nov09)
leroybrown
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 Posted: Thu Feb 18th, 2010 14:20

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Anyone standing out naked studying their shadow (in Canada in winter) needs serious help.

On the Dr Oz show yesterday they went on and on about how people should take gobs of Vit D, it was a show about Epstein Barr virus.



____________________
Autoimmune Pure Red Cell Aplasia, Jan 2009, Agranulocytosis 1991
Jan 14: hgb: 84, wbc 1.1
25D = 25 1,25D = 58 Aug 18/09
Phase 1: Sept 29/09 benicar 40mg q8hrs * Nov 26/09 40mg q6hrs
Freddie Ash
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 Posted: Thu Feb 18th, 2010 17:21

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HI LEROY & ALL

This is Fred in WV.  I saw some of that Dr Oz show.  It scared me to even hear the way he was pushing the vit-D this time.  He even did vit-D tests on the people at the show and told all of them that 76% of them were low on vit-D.  This is getting to be very, very scarey.

Remember, we are all in this together and I am pulling for us.

Your friend in Sarcoidosis
Freddie



____________________
Freddie: dx-sarc 2/82 lymph; skin, eyes, joints, esophagus, intestines, spleen, heart,lungs-meds digitek, L-thyroxine, nexium, furosemide, nattokinase36mg,eat cinnamon w/meals,25D-7; 125-D43
Sunset
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 Posted: Thu Feb 18th, 2010 21:36

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The Vit D pushers will continue promoting it as long as it is profitable to sell lab tests for VitD, sell VitD supplements and treat all the disease states that go along with VitD induced immune system suppression. It is so sad that the quality of human life matters not to the corporate health industry. Its bottom line is to make money, money, and then some more money!

Only when a majority of medical practitioners recognize that VitD is harmful to people will the medical industry bail because only then will they have a reason to do so.

Think of all the food labels you see on the market now that advertise "No trans fats" because trans fat containing foods don't sell very well anymore! People know better than to eat a diet high in trans fats. Just last week I saw a label on Thomas' English muffins for "No high fructose corn syrup" (HFCS). The message about the ill effects of HFCS is out in the media now too. It will be a happy day for me when I finally see labels on food item that say "No Vitamin D"!

Best regards,
Sunset :cool:

Last edited on Thu Feb 18th, 2010 22:38 by Sunset



____________________
FM, CFS, migr HA, low adrenal, RBC coinfection 11/07 1,25D70, 25D48, 7/08 25-D 21;11/08 25-D 22; 2/09 25-D 15.6; 7/09 25-D 11; 10/09 25-D 5ng/mL. olmesart 40mg+20mg SL, T4 25mcg QAM, T3 7.5mcg BID. NoIRs/limit lite exp
Alejandro
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 Posted: Sat Feb 20th, 2010 07:59

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Bane wrote:
Vitamin D and endocrine diseases

http://www.ncbi.nlm.nih.gov/pubmed/19768253

" In obese individuals, the impaired vitamin D endocrine system, characterized by high levels of PTH and 1,25(OH)(2)D(3) could induce a negative feedback for the hepatic synthesis of 25(OH)D and also contribute to a higher intracellular calcium, which in turn secrete less insulin and deteriorate insulin sensitivity. In hypertension, vitamin D could act on renin-angiotensin system and also in vascular function."

Recently, on a german forum a similar case was reported:

An obese individual with high PTH and "Vitamn D deficiency" received an injection of Vitamin D (not clear if 25D or 1,25D). The patient hat normal Glucose values. Morning Glucose was 60-80 mg/ml, after the Vitamin D Therapy, the glucose values in blood has risen to 120-130 mg/ml and they do not decrease, also a diabetic behaviour. This happened only after the Vitamin D Therapy and not before.

Endo does not have any idea why this happened.

Vitamin D has still many unknown aspects..

Alex



____________________
Skin Sarcoidosis treated with Corticoid creme 1,25 D3 : 41 pg/ml (was 63 pg/ml) 25 D :10 ng/ml (was 22 ng/ml)
MP since Dec 2009. Benicar q8h 50mg Mino
Bane
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 Posted: Tue Feb 23rd, 2010 12:21

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Vitamin D treatment in hemodialysis patients with low serum levels of parathyroid hormone: which is the best choice?

http://www.ncbi.nlm.nih.gov/pubmed/20175051

"Treatment with oral calcitriol (1.25D) was associated with a decrease in the serum levels of ALP and 25(OH)D"



The impact of vitamin d on dendritic cell function in patients with systemic lupus erythematosus.


http://www.ncbi.nlm.nih.gov/pubmed/20169063

"Our results suggest that vitamin D supplementation will contribute to restoring immune homeostasis in SLE patients through its inhibitory effects on DC maturation and activation."

 

Assessment of vitamin D status in healthy children and adolescents living in Tehran and its relation to iPTH, gender, weight and height.

http://www.ncbi.nlm.nih.gov/pubmed/20166840



 

 

Last edited on Tue Feb 23rd, 2010 12:31 by Bane



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Oral Lichen Planus(mild)/Clubbed Finger (digital clubbing)Last 25D 5.6ng/ml, phase3
Bane
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 Posted: Wed Feb 24th, 2010 22:45

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The Miracle of Vitamin D: Sound Science, or Hype?

http://well.blogs.nytimes.com/2010/02/01/the-miracle-of-vitamin-d-sound-science-or-hype/

“Correlation does not necessarily mean a cause-and-effect relationship,” said Dr. JoAnn E. Manson, a Harvard professor who is chief of preventive medicine at Brigham and Women’s Hospital in Boston.



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Oral Lichen Planus(mild)/Clubbed Finger (digital clubbing)Last 25D 5.6ng/ml, phase3
Lottis
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 Posted: Thu Feb 25th, 2010 06:48

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YES

Although numerous studies have been promising, there are scant data from randomized clinical trials. Little is known about what the ideal level of vitamin D really is, whether raising it can improve health, and what potential side effects are caused by high doses.

And since most of the data on vitamin D comes from observational research, it may be that high doses of the nutrient don’t really make people healthier, but that healthy people simply do the sorts of things that happen to raise vitamin D.

 

Last edited on Thu Feb 25th, 2010 06:57 by Lottis



____________________
HTN,LVH,CHF,arrhythmia,hypercholesterol,IBS? fibromyalgia?salivarystones,gallstones,ect...|15feb-07 init. 1,25D 37,5,|25-D 7,8(latest 15/2-07)| Ph1 29/7-08| Palliativ Meds. at the present; |Zoloft|NoIR's|covered up|disabled|
Rico
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 Posted: Fri Feb 26th, 2010 00:14

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Vitamin D Receptor Inhibitors Block Prostate Cancer Growth

http://endo.endojournals.org/cgi/content/abstract/en.2009-0991v1

Vitamin D receptor (VDR) agonists have been shown to reduce the growth of several prostate cancer cell lines.

Last edited on Sat Feb 27th, 2010 01:54 by Rico



____________________
No diagnosis/some symptoms; wife with Sarc on MP; Olm 40mg q6h| avoid D| 1,25D=63 25D=32 (May 2006) 1,25D=44; 25D=10(Dec 2006)PhaseI(May06) PhaseII(Aug06) PhaseIII(Aug07)
ChrisMavo
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 Posted: Fri Feb 26th, 2010 06:08

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In this interesting study they found no significant improvement in neuromuscular function with vitamin D supplementation after 16 weeks! 

I could have told them how much vitamin D helped ME!!!  Gave me ALS is all it did for me! 

Once-weekly dose of 8400 IU vitamin D3 compared with placebo: effects on neuromuscular function and tolerability in older adults with vitamin D insufficiency

http://www.ajcn.org/cgi/content/abstract/ajcn.2009.28113v1?maxtoshow=&hits=10&RESULTFORMAT=&author1=Lips&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT




Last edited on Fri Feb 26th, 2010 06:16 by ChrisMavo



____________________
PLS/ALS, speech difficulty, dizziness, leg weakness, overly emotional, Ph1Aug2609, 11/09: 25D-20, 9/09: 25D-27, 7/09: 25D-38, 1,25D-46, Mod Ph2Oct09, 100mg Mino + 150mg Clindy
NickBowler
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 Posted: Fri Feb 26th, 2010 13:44

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Heart missed a beat when I saw that headline Rico. I guess the editor doesn't realise the difference between an agonist and an inhibitor!



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Sarcoirodis CIDP, MP start 11/07, NoIRs, 02/08 25D-8, Ph3 since 07/08|

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