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Kas
Member in Phase 2
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Posted: Tue Feb 5th, 2008 19:30 |
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Can your blood type actually change?
I thought it was one of those things you were born with.
I am an AB+ and in my youth, was a regular blood donor. Hope I never passed TH 1 illness onto anyone in my quest to save lives.
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Sarc Dx by splenectomy 03- Lungs, lymph nodes, liver. Non MP meds: natural progesterone cream three weeks a month; cal/mag; probiotics; milk thistle daily; cranberry caps prn; quercetin prn.Noirs outdoors and under flourescent work lights, Spectra 3 cream
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eClaire
Member in Phase 2
| Joined: | Mon Sep 25th, 2006 |
| Location: | Virginia USA |
| Posts: | 550 |
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Posted: Tue Feb 5th, 2008 20:03 |
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| Not O. Had major irritability to St. John's Wort and also to Celexa and Wellbutrin. Nearly identical symptoms for all three. Claire
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CFS FMS MCS COPD hypermobility IBS/GERD osteoporosis 125D48 25D8 Ph1Dec06 ModPh2Jun07 NoIRs limited outings covered up low lux home abx brk 3/2/08 to 5/25/08
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prugg21
Health Professional
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Posted: Wed Feb 6th, 2008 00:02 |
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Isn't it interesting how St. John's wort is also capable of causing light sensitivity?
I'm O+, tried it for insomnia which it didn't help and got depressed instead. I also got depression from trying elavil for insomnia.
Pam
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MCS/CFS/FM,22+yrs,Gerd,migraines,insomnia,avoiding light & D,NoIRS,benicar 3/30/06 40mg Q4-6H,mino,4/18/06,mod/ph2-
10/17/06,probx,estriol, 3/06-25D=27,9/06-25D=26,11/06-25D=21,4/07-25D=22,7/07-25D=19
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Carricol
Member in Phase 2
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Posted: Wed Feb 6th, 2008 00:25 |
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St. John's Wort did not do anything for me either. I know it works for some people. However, there seems to be several individuals in this thread that have not benefited from it.
Is it possible that this is a possible marker for Th1 infection?
The hypothesis would go like this: If you suffer from depression and are not helped by St. Johns Wort you are more likely than the general population to suffer from Th1 infection. Would anyone like to study this or comment on it.
Last edited on Wed Feb 6th, 2008 00:26 by Carricol
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Sarcoidosis 125D38 Ph1 Nov07, fluoxitine Lithium Synthroid 5-HTP tyrosine digestive enzymes, NOIRs lite exp r/t commute cover up, Ph2 Jan08 25D9 Feb08
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jcwat101
Research Professional
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Posted: Wed Feb 6th, 2008 03:46 |
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I rather doubt one would have to react negatively to St. John's wort to qualify as Th1. I think most cases of depression have some degree of Th1 disease. Among Th1 people I know, some find an anti depressant that relieves their depression and others can't find any that work.
Joyce Waterhouse
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20 yrs with CFS/FM/Lyme/IBS, food sensitivities; 1,25D/25D 8/04:64/11 1/05:22/6 9/05:1,25D=12 10/06:22/8, 4/07:25/<4 chewed Ben. 40mg q8h; Mod. P2: 2/23/05, P2: 4/06; P3: 1/1/07
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NickBowler
Member in Phase 3
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Posted: Wed Feb 6th, 2008 08:56 |
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The blood type is just a genetic marker for a bunch of other important metabolic and immune related genes at the same chromosome locus. The phenomenon is known as 'linkage disequilibrium' - you can read about it in a fairly clear description here:
http://www.economist.com/science/displaystory.cfm?story_id=10283306
Blood type O (at chromosome locus 9q34), and particularly ABO-nonsecretors (at 19q13) both of which are recessive phenotypes, have associations with auto-immune prone individuals according to Dr.D'Adamo:
http://www.dadamo.com/forum/archivea/config.pl?read=90479
There may be an over representation of these two markers in the MP cohort, particularly amongst those with frank so called 'auto-immune' disease.
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Sarcoirodis CIDP, MP start 11/07, NoIRs, 02/08 25D-8, Ph3 since 07/08|
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Dr Trevor Marshall
Research Team
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Posted: Wed Feb 6th, 2008 14:03 |
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There may be an over representation of these two markers in the MP cohort, particularly amongst those with frank so called 'auto-immune' disease
Or Dr D'Adamo may be completely wrong.
I have no data, I am just reminding us all of the alternate hypothesis.
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NickBowler
Member in Phase 3
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Posted: Wed Feb 6th, 2008 14:28 |
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I don't think his work goes as far as making any hypothesis of a mechanism for auto-immunity such as you have made with the VDR associations. It is merely that he has noted a link, and blood types are easily measurable parameters so could be of some usage to the MP cohort later on. There are no doubt many other gene locii involved as well, the MHC on chromosome 6 is often cited as being involved with auto-immunity for example. Certainly his work in no way contradicts yours, hopefully it will supplement it further down the line
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Sarcoirodis CIDP, MP start 11/07, NoIRs, 02/08 25D-8, Ph3 since 07/08|
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B R H
Member in Phase 3
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Posted: Thu Feb 7th, 2008 18:47 |
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| I also tried St. John's Wort in fairly high doses for at least a few months after reading (or mis-reading) something about it helping nerve regeneration. This was after my spinal cord injury. Ever since then I sunburned much easier although I didn't really start getting ill from sun exposure until after the tick bites. I've always wondered if the stupid SJW experiment caused permanent damage to something in my skin.
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Lyme, babesiosis, hypothyroidism, asplenia, incomplete quadriplegia, 125D58 (11/06), 25D12 (01/08), Synthroid 50 ug qd, sunscreen & sunglasses outdoors as needed.
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Lottis
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Posted: Sat Feb 9th, 2008 09:04 |
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Coffee is closely related to the Solanaceae phylogenetic tree http://www.sgn.cornell.edu/about/about_solanaceae.pl which are causing the nightshade intolerance of the immune system. It has been found that some of these plants produce 1,25 D, according to this article: http://noarthritis.com/vitaminD3.htm
and this
http://dx.doi.org/10.1016/0031-9422(95)00883-7
/Lottis
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HTN,LVH,CHF,arrhythmia,hypercholesterol,IBS? fibromyalgia? achne rosasea e.c.t.|15feb-07 init. 1,25D 37,5,|25-D 7,8(latest 15/2-07)| Ph1 29/5-08|Med;verapamil|carvedilol|Furix|Stesolid|Cymbalta|Magnyl|NoIR's|covered up|disabled|
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NickBowler
Member in Phase 3
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Posted: Sun Feb 10th, 2008 15:11 |
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Foods don't necessarily have to contain vitamin D or vitamin D analogues to affect important receptors like the VDR. For example this gigantic molecule can behave as an insulin mimic and strongly binds to the insulin receptor:
http://160.114.99.91/astrojan/protein/pictures/agglutin.gif
http://www.pnas.org/cgi/reprint/70/2/485.pdf
WGA has been implicated in insulin resistance as these molecules are not easily cleared from the body (apologies to all you pasta lovers)
There may be other glycoproteins lurking in common foods which bind the VDR.
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Sarcoirodis CIDP, MP start 11/07, NoIRs, 02/08 25D-8, Ph3 since 07/08|
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wrotek
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Posted: Wed Feb 13th, 2008 00:08 |
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Interesting case reports about coffee drinking and anxiety.
Switching to tea eleminated it, so it can't be a caffeine that causes it.
http://www.healthcentral.com/anxiety/c/8146/5936/comments/
I began having chronic anxiety and panic attacks during a very stressful period in my life. As time passed and the stresses went away, my anxiety got much better, but never fully left. For years I lived with a the constant sense of dread and that feeling that something was off. I had medication in case of emergency, but I rarely took it. I am not a person who is comfortable taking medication on a regular basis and I never wanted to be dependent on a substance to get through the day. So I lived with it.
I stopped drinking coffee because I noticed that it was making me feel a bit nauseated on a regular basis. I didn't remove caffeine completely -- I started drinkine tea instead. It was about two weeks without coffee when I realized that the anxious feeling was gone. Completely. The ONLY change I made in my life at the time was cutting out the coffee. That was more than two years ago and the anxiety has never returned, even in stressful situations. It may sound crazy, but I'm a firm believer that coffee was the cause of my anxiety.
from comments
I'd get an intensely paranoia about my relationship (with a great guy and completely unfounded), and a general sense of anxiety and panic. It only occurs after having drank coffee. I switched to a stronger green tea/pomegranate drink (a few cups each morning) and have eliminated that awful feeling of dread/paranoia/pani A month ago, I stopped drinking coffee because of extreme anxiety/ panic attacks related to relationship problems. I started drinking tea and found I could deal with the stress more easily without the physical effects. Today I had coffee with a friend this morning and found that anxious thoughts I was having before came quickly back. No more coffee! I have had the exact same experience Linda. When i was drinking coffee regularly, i was getting panic attacks. I recall one time that i did not want to go the local carnival, because i was in no state of mind for it. My girlfriend thought i was going a bit funny but also understood there was something wrong. As soon as i switched to tea the panic and anxiety dissappeared. Last edited on Wed Feb 13th, 2008 00:20 by wrotek
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Lyme reflux chronic pain fatigue depression 125D36 Ph1Sep05 Ph2Oct06 Ph3Apr07 homebound in low lux NoIRs 25D<7 Oct06
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maggie weeks
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Posted: Wed Feb 13th, 2008 00:45 |
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| Correct me if I am wrong but I thought tea had as much caffeine in it as coffee. I have read that coffee cuts oxygen to the brain by 20%. May be that is why people are having panic attacks?? Just thought. I have never been a coffee drinker but have suffered from anxiety.
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Bartonella muscle pain weak pelvic instab neck instab Lumbar nerve demyl occip headaches thoracic pain| Clonazepam Celexa 40mg| CutD&light 5/05| BeniQ6H Oct05| 1,25D=54 25D=29/ Apr06 25D=15| Mino Nov05| Phase 2 Apr06
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Kas
Member in Phase 2
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Posted: Wed Feb 13th, 2008 01:24 |
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| Strangely, when I do have the odd cup of coffee to bump my BP up when it is super- low, I feel really good! It certainly does not seem to lessen the oxygen to my brain, and in fact, it makes me feel far more energetic. I only have about a cup once a week or less. Regular tea has no effect on my BP and oddly, I can no longer eat my beloved dark organic chocolate - it drops my BP even further!! I suppose we are all different in what affects us.
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Sarc Dx by splenectomy 03- Lungs, lymph nodes, liver. Non MP meds: natural progesterone cream three weeks a month; cal/mag; probiotics; milk thistle daily; cranberry caps prn; quercetin prn.Noirs outdoors and under flourescent work lights, Spectra 3 cream
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Dr Trevor Marshall
Research Team
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Posted: Wed Feb 13th, 2008 15:26 |
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I deleted two posts which had wandered into the realm of speculation, repeating common pragma about the mode of action of caffeine.
Please keep this thread on-topic, focused on the immune activities of chlorogenic acid.
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shamutooth
Member in Phase 3
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Posted: Mon Feb 18th, 2008 13:13 |
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| Since quitting coffee I have tried a cup a couple of times.I get the worst feeling which is hard to describe,sort of like an extreme nervousness/anxiety,and a creepy crawly sensation in my skin,along with insomnia.Is it the caffeine? HELL NO!!! I take a 200 mg caffeine pill and drink 4 cans of Diet Coke sweetened with Splenda, daily,and have no insomnia or weird sensations.Tea gives me the same sensation,but on a smaller scale. Last edited on Mon Feb 18th, 2008 13:39 by shamutooth
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MCS,CFS,IBS,insomnia,anxiety,depression,started Doxy July'04, MP Sept. 04; Benicar 40mg 3/day; Phase 2 started 2/2/05; 6/28/05 D results 25D=29,125D=47;11/13/05 25D=10
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maggie weeks
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Posted: Wed Mar 12th, 2008 00:02 |
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| Can you get me up to date please I followed your advice ages ago and started drinking Roobis tea, is that a no no now? Are all teas bad, what about herbal teas?
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Bartonella muscle pain weak pelvic instab neck instab Lumbar nerve demyl occip headaches thoracic pain| Clonazepam Celexa 40mg| CutD&light 5/05| BeniQ6H Oct05| 1,25D=54 25D=29/ Apr06 25D=15| Mino Nov05| Phase 2 Apr06
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Dr Trevor Marshall
Research Team
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Posted: Wed Mar 12th, 2008 01:33 |
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Maggie, I have no idea what 'Roobis tea' is, and am certain that I have never suggested its use.
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maggie weeks
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Posted: Wed Mar 12th, 2008 02:38 |
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| Hi Trevor! I spelt it wrong!!It was Rooibos caffeine free amd I must have dremt up that you drank it with your Benicar to help it" diffuse better in the tissues." I am usually pretty good about following your ideas so maybe the new spelling will ring a bell!! Question, do all teas have to be avoided now?
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Bartonella muscle pain weak pelvic instab neck instab Lumbar nerve demyl occip headaches thoracic pain| Clonazepam Celexa 40mg| CutD&light 5/05| BeniQ6H Oct05| 1,25D=54 25D=29/ Apr06 25D=15| Mino Nov05| Phase 2 Apr06
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Reenie
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Posted: Wed Mar 12th, 2008 03:03 |
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Rooibos, often called "red tea", because of the color released during brewing, possesses a flavor similar to that of black tea. Also, like black tea and green tea, Rooibos provides beneficial antioxidants-but without the caffeine.
The brand Good Earth original tea is mainly made from Rooibos (Masai) tea.
HERE are one of the links I found that contains a little more info about Rooibos tea. 
PS I think you're thinking of Trader Joe's jasmine green tea that Dr M drinks. Last edited on Wed Mar 12th, 2008 03:05 by Reenie
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