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The Marshall Protocol Study Site > PROF. MARSHALL'S PERSPECTIVE > Prof. Marshall's Perspective > The Common Cold is really Immunopathology? |
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Dr Trevor Marshall Research Team
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"It might be hard to believe, but the "normal" virus infection might not be as "normal" as science has hitherto believed "Common Cold Symptoms Caused By Immune System -- Not The Cold Virus" http://www.sciencedaily.com/releases/2008/10/081029101201.htm That is just another reason that we keep telling people to always assume that what you are feeling is IP, unless suggested otherwise by Doc's work-up or bloodwork |
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Sunset Health Professional
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Very interesting article. Now when researchers finally concede that your "Vit D" research is indeed valid they will have the most important piece of the immune system figured out. And they will have the necessary tools available to effectively treat patients Sunset |
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expate Member in Phase 3
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In explaining part of the MP to those who will listen to me Everyone seems to relate to that, so I thought it was common knowledge. I guess this study is a more in depth confirmation that this is the case. Odette |
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lhebel Member in Phase 2
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I'll bet that is why I didn't have a cold for years prior to starting the MP when earlier in my life I had 3 per year or so. My immune system wasn't functioning! |
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Rico Moderator
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On the other hand, I was getting about 2 colds and one bad flu each year. I haven't had one since I started the MP. |
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paulalbert Board Staff
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http://mpkb.mp-dev.com/doku.php/home:protocol:immunopathology |
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Freddie Ash Member in Phase 3
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HI ALL This is Fred in WV. Thanks for all this info about a cold, but I would like to add to this to this discussion, the fever blister. I think it is caused by the TH1 diseases and the virus moves in after the sore comes out on the lips. I have had a lot of lip IPs since I have been on the MP. I use to get fever blisters when I was in grade school just before it started. I guess the stress for me having to go back to school after the summer vaction. Maybe some one can find a site that also shows this too. Remember, we are all in this together and I am pulling for us. Your friend in Sarcoidosis Freddie |
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Rico Moderator
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Ah, I'd forgotten about cold sores. I used to get them frequently and they'd take a while to go away. They've decreased significantly since I've been on the MP. In fact, I don't really remember the last time I had one |
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Caitiegirl Member in Phase 2
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My husband and one of my sons gets cold sores every autumn. They have even figured out that sun exposure seems to be the trigger. Things just seem to become clearer and clearer. Can't wait to see what 2009 will bring! Mindy Paul, The link is amazing. Everything looks so great. Can't wait for all this to be fully operational. Last edited on Sun Jan 4th, 2009 02:33 by Caitiegirl |
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carol Moderator
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The seemingly contradictory comments on incidence of viral illnesses by those on the MP has always puzzled me. Some people say they were sick all the time and now that they are on the MP, they never (or hardly ever) get a cold, etc. Others report just the opposite: they gleefully describe getting their first “normal” cold in years and attribute it to immune system recovery produced by the MP. Anyone have additional insight on this phenomenon? Carol |
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Caitiegirl Member in Phase 2
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My family has one person on the protocol, three who have cut D and are waiting to start the protocol, and 2 who are happily ignorant and oblivious to it all. My husband is a diabetic and addicted to Vit D foods. In the last year we have found that the 2 who are ingesting D have averaged a cold each quarter. My husband has had a constant sinus infection for the last 5 months and will see an ENT next week. Oldest son is relatively healthy but is also having at least one cold/sinus infection each 3-4 months. My other 2 sons who have drastically cut D but not totally taken it out of their diet have been sick once this year. This is a drastic reduction for our family. I have only been sick once, with pneumonia. I did not have a cold or sinus infection first. Caitie kept telling me I was herxing. Caitie has had some runny nose IP and some short-lived symptoms but all seem to have been IP. None lasted more than a couple of days and came and went with the antibiotic dosage. In the past we were one of those families that stayed sick all winter long. This may have been the healthiest Christmas for the kids and I ever. But all those stubborn ones who won't give up D were seriously sick. Maybe someday they'll figure it out for themselves. Mindy |
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carol Moderator
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The seemingly contradictory comments on incidence of viral illnesses by those on the MP has always puzzled me. Some people say they were sick all the time and now that they are on the MP, they never (or hardly ever) get a cold, etc. Others report just the opposite: they gleefully describe getting their first “normal” cold in years and attribute it to immune system recovery produced by the MP. Anyone have additional insight on this phenomenon? Carol |
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Guss Wilkinson Member in Phase 3
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One of my herx symptoms is a constantly runny nose (which varies in intensity), especially when I do anything physical. But in terms of having a cold (as I used to get), I cannot remember the last one I had...must be years, and that is despite people dropping like flies around me. Cheers Guss |
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jcwat101 Research Professional
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It may be more complicated than this, but perhaps one way of looking at it might be -- if you are very ill, you don't ever get colds (I was at this stage at one time), then if you improve to moderately ill, you get colds fairly often, and then when you are really well, you don't get them hardly at all (perhaps the immune system is so strong it wipes them out before they even multiply enough to produce any noticeable immune reaction). And then it just depends on where you start when entering the MP, whether you get more or less colds. I think that the ultimate endpoint for us all when we get really well is to not get colds at all Joyce Waterhouse Last edited on Mon Jan 5th, 2009 05:28 by jcwat101 |
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carol Moderator
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Brilliant, Joyce! |
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Alayne Member in Phase 3
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Thanks for asking that Carol; I've been wondering the same thing for a while. And thanks for the succinct and understandable answer Joyce! I currently have a cold. My second one in a year. I did not catch colds for years pre-MP (however, I seemed to catch everything else). I'll admit that I've not exulted in my ability to catch colds again, but have wondered about the changed immune system response, as my cold of about 9 months ago was quite different than now. The cold earlier this year hit me harder than those around me. In contrast, this week's cold is lingering, but I only really felt lousy for a day. My brother and father who've caught it are experiencing major symptoms and have been down for the count for over a week. So I wonder if I'm heading into that upper echelon of wellness that Joyce speaks of. It's nice to think about, to be sure. Cheers, Alayne |
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UshiAad Member in Phase 3
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For what it’s worth, my experience with the cold, for me it is one of THE symptoms to monitor my progress on the MP. Pre-MP and while on the MP could not get a normal cold or fever, although i felt like a balloon at times due to the viral (?)load. It felt like i got a cold but my body, ie immune system, was not able to respond. Like it was in a valley and couldn’t climb the mountain. Since a couple of years can sneeze again and only recently i started to develop a runny nose and some mucus (first time in 16 years !).....and i feel so much better |
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Afternoon Tea Member in Phase 3
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I understand the concept of failing to have an immune reaction to a cold thus being really sick, but wouldn't that result in dangerous illnesses? Isn't that basically the problem for people with "boy in a bubble" type syndromes? How can we be so sick that we just don't get a cold or flu yet not have any immediate repercussions? I don't get that. I'm just recovering from my first head cold in ages right on the heels of the first stomach flu I have had in ages. My son had it at the same time and observed that this was the first time he ever remembered me being sick when he was. He is 15. I have had some minor cold symptoms from time to time but not enough to stick in his mind. I don't think I have had any true stomach flu symptoms in a decade or more until now. I agree with UshiAad about feeling like I can't run a solid fever or "climb a mountain." Weird. Another related question. Why do some people have a break in their other symptoms when they are sick with a virus or cold whereas with others their regular symptoms get worse? For me I had a break in joint pain while sick that was actually quite a treat. How sad is that??? |
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expate Member in Phase 3
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Well, I think all of these questions have a common question. It's one I've asked, as an outsider to both medicine and science. What is the disease pathway? What makes us sick, both for accute infection and in autoimmune diseases? My point? OK, so we have these slow growing CWD bacteria. We're fine-ish for years. Then we full blown get "a" disease. Why? Is it compromised immune system? Well, not only. I mean, I think, and I'm making this up here, but I think there must be some critical mass point when the die off that causes IP when your killing the bugs, comes in to play. Like, I have such a huge bacterial load that just supporting their life/death cycle causes my symptoms and not my immune system's reaction. I don't know if I'm making sense, but I think we need to distinguish between IP and disease and therefore understand what causes the symptoms of disease before we activate the immune system. Or have I had too much wine? Odette |
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jcwat101 Research Professional
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As to Afternoon Tea's question, I would mention what a retired cold expert I know told me. He said the most common cause of colds, the rhinovirus doesn't damage epithilial cells -- so it isn't really harming the body's cells. Another interesting thing he told me was that 25% of colds are asymptomatic. Some people can clear a cold virus without getting any symptoms -- they will find the person is shedding the virus etc... and they will have no symptoms at all. I suspect that the imbalance in the immune response caused by the colds is what can lead to complications that arise from colds. So, just because one doesn't get symptoms of a cold, doesn't mean one doesn't clear the virus. I also found a study that showed that people who have Parkinson's Disease almost never have colds and even in the years before they get Parkinson's Disease, they don't tend to have colds. Anyway, I think it is more complex most likely than what I have stated in my posts, but it seems that whether or not one gets colds is not a simple linear reflection of one's state of health. I don't really understand expate's question, so will leave it with the above statement and suggest we not get too worried about this issue. Joyce Waterhouse Last edited on Wed Jan 7th, 2009 05:01 by jcwat101 |
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expate Member in Phase 3
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I will try to figure out what it is I'm trying to ask. Arrrg, I do find it frustrating that this forum is all typing. I think I do better when I actually converse with a person. I know I'm making ignorant assumptions, not having any basic understanding of science, that could get me on the path to sensible questions if I could just have a conversation. Ah well, I've tried to express myself. Sorry, I'm just not that capable. Odette |
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edj2001 Moderator
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jcwat101 wrote: and then when you are really well, you don't get them hardly at all (perhaps the immune system is so strong it wipes them out before they even multiply enough to produce any noticeable immune reaction).... WOW Joyce! Great ideas. Soooo, the MP maybe a cure for the common cold as well!!! That would be great. Think how much research money has been spent trying to find that "windmill" to no avail. I didn't experience colds or flu for years either before the sarc presented. Now I seem to get one a month (being around grand children). Looking forward to that ultimate end point you describe. Gene |
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Fred Member in Phase 2
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I haven't had a cold for nearly 30 years. I'd love to have one! |
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Aunt Diana Moderator
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If a cold is really immunopathology...then, I take that to mean the immune system is working, therefore you have cold symptoms. If the immune system is not working, no cold symptoms. (Explains to me why so many people with serious illlness say they never get colds) I don't really understand what Odette is trying to ask....but if it's what I think it is....perhaps what she is calling "disease" is simply an accumulation of too many CWD or other types of bacteria or virus. Requiring another type of antibiotic to help the immune system fight it off. What other kind of disease is there? |
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Rico Moderator
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So, since I've never thought of myself as being seriously ill as most people on the MP are, although I realize now that my illness was worse than I thought (depression, brain fog and anxieties among the worst), I guess that would mean that since I was having frequent colds every year, my immune system was still working? I haven't had a cold since I started the MP, for 2.5 years now and I have seen improvements. |
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Over-Heated in PHX Member in Phase 2
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My experience is like that also, Rico, with Morgellons lesions on top of the stack. Here, is it not important to seperate the concept of the adaptive and innate immune system? If our innate immune system was operating, would our adaptive immune system really get an opportunity to be called to battle? Could this be a reason that people have what seem like opposite responses? As in, if the innate immune system has begun to operate, might it prevent the need for an adaptive immune response (cold symptoms). Still, Last edited on Wed Jan 7th, 2009 19:54 by Over-Heated in PHX |
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NorCalJim Member in Phase 3
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I've also been puzzled by the fact that prior to the MP I hadn't had a real cold for about 8 years. Of course I must have been exposed to just as many bugs as everyone around me so I'm not sure why my immune system never responded to them or how or if I cleared them without any symptoms. Since starting the MP, I've had more colds and sinus/eye/ear infections in the first 20 months than the previous 10 years. Joyce's explanation seems to fit my situation pretty well so far... NorCalJim |
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Bane Member
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jcwat101 wrote: As to Afternoon Tea's question, I would mention what a retired cold expert I know told me. He said the most common cause of colds, the rhinovirus doesn't damage epithilial cells -- so it isn't really harming the body's cells. Makes sense 1: Very high cwd (microbiota) load: likely to not react to the viruses like the Rhino, if you get a harmful virus you might die from it. 2: High cwd load: might react to the Rhino, the virus are able to grow on mass before immune system kicks in, you end up having the cold a long time. 3: Moderate cwd load: likely to get the cold, viruses are able to grow on mass, immune system catch on quicker than those with high cwd load. Your not sick as long, but more violently than those with high cwd load. 4: Low cwd load: Sometimes you get sick, but not as violent as those with moderate load, and you clear the virus pretty quick 5: Very Low cwd load: you get infected, but clear it before it reaches large amounts in your body, leaving you without symptoms (quick and effective). ?? Last edited on Wed Jan 7th, 2009 23:02 by Bane |
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geirf Health Professional
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Among parents with Autistic children it is a common observation that their child never have any cold or flu when others do have. To them it is a sign of getting healthier when after som treatments most often chelation their child like others get a common cold, thought of beeing a sign that immune system have started react like it should.. Geir Flatabø |
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jcwat101 Research Professional
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I think what Bane says may be pretty much the case. However, the very very high CWD load may not exhibit as the person appearing very very sick. It may not be simply correlated with total load, but the nature of the bacteria and immune system factors. That may be why I know a couple people who almost never got colds even as children, and later developed sarc or multiple sclerosis. They weren't obviously very sick as children or young adults and worked full time etc..., but the process was definitely operating as shown by the serious illness apparent later (also like the Parkinson's cases). As to expate's question, I think what you are asking isn't necessarily clearly known for many diseases, because we don't know how much CWD most people have when they come down with these illnesses or the role it is playing. So, the diseases have not been studied from that perspective. Maybe most of the diseases people get, they would avoid getting or clear easily or even asymptomatically, if they were free of CWD and had an optimally functioning immune system. I don't really know. And each disease is different. In some diseases, the organism produces very toxic products or has other virulence factors that play a very important role. I borrowed an infectious disease textbook from a medical library and it was extremely heavy -- could barely carry it (and that was only one volume of a two volume set -- with very thin pages and tiny print) Influenza is different from rhinovirus (it apparently can damage cells), but I did just read that only 2 out of 3 people who acquire influenza exhibit symptoms of it -- yet they are just as infectious as anyone else and apparently they clear it just fine. Joyce Waterhouse Last edited on Wed Jan 7th, 2009 22:44 by jcwat101 |
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Bane Member
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sorry for mixing the cold with the flu (edited). Yea i think your right, it's way more complex. I like the answer Trevor gave to the Brazilian doctor who asked at ICA2008 if all humans have the microbiota. Trevor's answers "Yes, all human beings have this microbiota. Not all of the microbiota becomes pathogenic." "Only those that collect a particular set of genomes that causes the human body to function in a way that is recognized as a disease" Last edited on Wed Jan 7th, 2009 23:51 by Bane |
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Rico Moderator
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Forgot to mention in my previous post that although I haven't been that ill and got frequent colds/flus prior to starting the MP, my wife who has been very ill and it's been said she must have a very high bacterial load due to the length of time it's taking her to progress on the MP due to the difficulty of IP, also rarely had colds prior to the starting the MP. |
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garyv Member in Phase 3
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I’ve been following this discussion with interest, trying to relate it to my own experiences. I've found Joyce's and Bane's explanations rather fascinating, although for me there seems to be at least one other factor involved, i.e., food. For my first 35 years I ate the SAD (Standard American Diet) and experienced colds and flus on a rather regular schedule, once in the fall and again in the spring when the weather would change. Always the sinuses would be alternately stuffy and runny and phlegm from the chest would start discharging after a few days. Sometimes there would be just a cold (no fever); usually it would be what we called “flu” (with fever) or maybe it was only a “bad” cold. It would usually leave after 7 to 14 days, with or without antibiotics, which I usually refused after my adolescent years. At age 35 (21 years ago) I started making rather radical dietary changes, first dropping dairy and many processed foods out of my diet. I noticed very soon a lessening of severity and duration of colds and flus, although they still came around at least once a year. Gut symptoms (bloating, cramping, loose stools, extreme fatigue-inducing discomfort) likewise began to ameliorate significantly. By 11 years ago I had dropped all grains, potatoes, vegetable oils and sweets of all kinds, adopting what’s known as a “Paleo” diet, i.e., eating only those kinds of foods available in a state of nature with a sharp stick or stone. Gut symptoms and flus (fever episodes) then completely ceased and colds gradually diminished in severity and duration, down to essentially one-day bouts of sneezing and runny nose, but never any color in the discharge or bronchial involvement as in pre-diet days. For the 10 months I’ve been on the MP, I’ve had 2 bouts of flu-like disability with fever, achy muscles and fatigue, although only the last one put me in bed (for 2 days on the 2nd & 3rd day after starting full dose Z). And, I’ve had a couple instances of diarrhea, apparently non-food related. But, there’s been no more gut or sinus symptoms like I had pre-Paleo. Here’s a quote from an enlightened veterinarian that I found helpful some years ago in understanding my experience: Principle number one: The foods that are bad for us are bad in numerous ways. The “four horsemen”...gluten (from the grains wheat, barley, rye), casein, soy, and corn terrorize us in more ways than simply inducing villous atrophy, which results in the chronic malabsorption of the essential nutrients that we have covered. These foods provide staggering levels of glutamate (and aspartate), estrogens, allergens, and lectins, and when prepared for consumption, act as carriers of many of man’s worst creations in the form of GMO’s, hormones, and chemical additives… The “four horsemen” induce immune suppression and incite chronic tissue inflammation and damage… Hmm—could it be that immune suppression (or perhaps overload of toxins?) by the “four horsemen” somehow helps the entrenchment of the CWD nasties, which Dr. Marshall has shown are the actual culprits which “incite chronic tissue inflammation and damage?” And is the rhinovirus or flu virus merely a trigger that sends the immune system into “clean-out” mode so that it can mount an effective response to the virus at the same time that it discharges through the lymph system the stored toxic waste from metabolically inappropriate foods? And can others avoid gut and sinus symptoms (immunopathology?) by diet restriction as apparently is the case with me? Raw Paleo Guy wants to know! |
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expate Member in Phase 3
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Over-Heated in PHX wrote: ...Here, is it not important to separate the concept of the adaptive and innate immune system? If our innate immune system was operating, would our adaptive immune system really get an opportunity to be called to battle?I didn't know we had more than one immune system. edited for typo Last edited on Sun Jan 11th, 2009 04:23 by expate |
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Bane Member
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http://en.wikipedia.org/wiki/Immune_system http://en.wikipedia.org/wiki/Innate_immune_system http://en.wikipedia.org/wiki/Adaptive_immune_system One system, different parts.) |
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expate Member in Phase 3
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Oh. Thanks, |
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Over-Heated in PHX Member in Phase 2
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Hi Odette, I sent you a message with my more rudimentary explanation that I wouldn't post to the main board! Try looking at the CWD - Cell Wall Deficient threads that are listed in the "C" section of the ABC's of the MP. I think that is where I got the story initially. Here is a link to the ABC's http://www.marshallprotocol.com/view_topic.php?id=2135&forum_id=32&jump_to=36159#p36159 Still, |
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KFaucher Member in Phase 3
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I wonder if these cold groups (many colds, no colds, normal colds) correlate with the reactions to Benicar (feel better, feel worse, no change)? |
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expate Member in Phase 3
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Interesting. How to explain the overall arch with the underlying anomalies? Odette |
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Rico Moderator
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Well, I guess I spoke too soon. For the first time in over 2-1/2 years (all of it on the MP), I caught a bad cold. Doesn't sound like a long time for many people, perhaps, but I used to get several a year. Well, my child (home-schooled) was exposed to a lot of kids recently after starting the first class of a new activity and caught a bad cold, including fever. Appears I got it from my child. So, not sure what this really means, but I'd guess part of my immune system must be working...? I guess I'll have to wait and see how long it lasts - they used to last a long time. I was also thinking whether my child had a flu or cold - well, my wife (also on the MP) has also caught this cold (found out this morning) - she thinks our child has a flu due to the nature and degree of symptoms. I would call mine a cold. But we all got this the same week. So, I would think that the difference between a cold and flu is simply the degree of immune response to it. Last edited on Sun Jan 25th, 2009 13:14 by Rico |
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MarkN Member in Phase 3
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I discovered that I can bypass a cold by taking a Benicar at any moment I feel a tickle coming on, or at least every 4 hours, whichever comes first. I still feel tired and foggy (immune system working) but avoid all the sore throat and snot side of things. |
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kenc Member in Phase 3
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I wouldn't be too quick to jump to the conclusion that you are avoiding a cold by taking SL Benicar. 1) How do you know that the cold symptoms you are getting are a sign of an impending cold? Perhaps, these are from some kind of immunopathology induced from the protocol. 2) How do you know there is a cause and effect. When I used SL Benicar to get rid of neurological symptoms, I purposely delayed the SL Benicar to ensure there was a cause and effect relationship. Delaying the SL Benicar delayed the remission of symptoms. Remission of symptoms took only a minute or two after taking the Benicar. I developed confidence in this cause and effect relationship. Perhaps it would be a good test to take Benicar for every other onset of cold symptoms. This should help to determine the correct conclusion. It would sure be wonderful if we could knock out a cold simply by taking Benicar. I suspect there will be lots of interesting effects discovered from re-activating the innate immune system with Benicar. |
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MarkN Member in Phase 3
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I think it does work, because I tried it when family members were sick, so I know it was a germ and not just IP. It is possible I wouldn't have gotten sick anyway. I have been on the MP for over 2 years. But normally I catch everything. It seems to help within 15 minutes, at least in a palliative way, but only for a tickle, not so much if you already have a sore throat. |
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Limburg Member in Phase 2
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Since I have MS,I havent't had a cold and/or fever. The first thing happening when on MP was a terrible headache,followed by a "cold" with fever! (I'm only 2 months on MP now) After 4 weeks I'm still coughing a lot,it seems as if my body wants to get rid of something in my lungs Other things are happening also,but this is the most significant so far. I could believe something's woked up in there Annemarie |
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eClaire Member in Phase 2
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I've just started reading this interesting thread and I think what is happening (generally) is how Bane explains it, and I also wonder about KFaucher's comment / question. I wonder about the experience of folk on the MP. Depending on where you might fall on Bane's continuum (if we applied a number to each point on the continuum) how might your response be to the protocol? For example, I know folk who felt worse but then turned around at a much faster pace than me (2 1/3 years in and I'm not turning the corner yet; however, the light I see at the end of the tunnel is no longer based on faith alone). I never had a cold, rarely had a virus (many years in between), could have had sufficient IP on Benicar alone, had out of control IP initially, and am back to Mino alone (waiting for my high kidney labs to clear). I'm thinking that we might see reactions to the MP that track where people would be on Bane's continuum. At any rate, it would be interesting to know as it might be somewhat predictive of the MP experience. Claire |
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Dogster Member in Phase 3
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Doesnt work for me. AS i got sicker and more chronic, the bugs became more frequent, lasted longer and also got more violent (with a greater of number symptoms showing up), -- so #1 and #2 and #3 dont hold up but #4 and #5 might . . . Just generally doesnt fit though . . . |
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carol Moderator
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I just reviewed this thread because my husband Phil, who is on the MP prophylactically, has a cold that just won’t go away. This discussion reminded me of something Dr Blaney brought up in my consultation with him last February: the general adaptive syndrome. Hans Selye pioneered the concept of the general adaptive syndrome in the 1980’s and Dr Blaney finds the model useful to describe how the immune system responds to the stress of infection by CWD bacteria, in its attempt to maintain homeostasis. As bacteria are killed, infected cells undergo apoptosis. This loss of cells and the release of cytokines produce immunopathology, which can be considered the actual “stressors”. According to the general adaptive syndrome model, in the initial stages of disease, the acute phase, the body responds with symptoms that come and go. When the body enters the adaptive phase, no symptoms are evident. This is followed by the degenerative stage, during which it is all downhill and the body is overwhelmed by disease. (I now have the book by Selye, “The Stress of Life”, and hope I understand this concept better after I review the text.) Carol |
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eClaire Member in Phase 2
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Carol you just described my descent into totally disability to the T. I watched over the years as my body adapted to various things--symptoms come and symptoms go--, including in the years before total disability where life-long allergies and serious reactions to chemicals just disappeared. Then I crashed totally and could feel my life slip slip slipping away. Now my health and life is returning to me. Life is good. Love life back. And thank God for Trevor Marshall and everyone at this site for helping me recover what was being lost (and have something one day that I have never known: good health). |
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