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Easy way to get smaller dose of antibiotics
 Moderated by: Dr Trevor Marshall  

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Martha
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 Posted: Wed Sep 15th, 2004 20:19

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I have 100 mg pelleted Minocin left over from my Harvard Protocol days and I'm just wondering how everyone is dividing them up.

Should I count each individual piece-yikes!!! And then try and do the math which was never my best subject - Or should I just guestimate????

Thank you, Martha



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Scleroderma resumed MP Feb07 after 2 yr hiatus due to pregnancy D2512 & D12545 NoIRS D25-8 (Sep07) Ph2Feb08
DON
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 Posted: Wed Sep 15th, 2004 20:33

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Hi Martha, if you are sticking to the standard amounts recommended in the Phase 1 protocol procedure it is just a matter of breaking the tablets into 1/4s or 1/2s to get the 25mg and 50mg amounts.

If you feel you are more sensitive to the protocol and have to go to lesser amounts than it is time to go to a scale and weigh out the mg amounts that you feel are appropriate.......Don


Meg's note: Tiny doses of minocycline are no longer recommended. Why have you change the starting dose of minnocycline?



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CFS/LUPUS/BEHCETS,1,25=44,Ph1July04,Ph2Sept04, Ph3 Nov04,25D=14 Nov07, Klonopin, Noirs, minimum light exp. coverup.
Reenie
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 Posted: Wed Sep 15th, 2004 20:34

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Martha,

I think alot of us have the powdered form. 

I read one post where I believe one person said he counted the amt of pellets in a cap. 

Then, after knowing this no, although it may slightly vary from one cap to another, he would just count out x amt of pellets for his doses, depending on the math. :cool: 

arlene couchman
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 Posted: Wed Sep 15th, 2004 22:51

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Hi Martha,

 It's Arlene. I empty the capsule onto a mirror. Then I use a one sided razor blade to divide the powder. I've gotten empty clear capsules at the health food store on St. George Blvd.  Open the capsule and push the desired amt. into the capsule with the blade. It's really easy. Good luck

                 Arlene



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sarc. Meds: Now taking Lexapro 10mg per day; Ambien 10mg nightly; Hydrocodone and Alprazolam occ. Dtest Jan. 19, 2007 - 1,25D=56; 25D=9. Avoiding D,light. wearing NoIRS. Beni comm Feb.6, 2007 Q6H, mino comm Feb.21, 2007 now up to 100mg every other day. Re
cenkog
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 Posted: Thu Sep 16th, 2004 15:43

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Really very good idea !

Lilly
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 Posted: Thu Sep 16th, 2004 20:37

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I'm doing capsules of powder, not pellets, but this might work for that, too: I put 1 cup of water in a jam jar, open the capsule and dump the 50mg minocycline in, put on the lid, shake well, measure out 1/2 cup, and drink my 25mg Mino. Refrigerate the rest until day after next.

For 100mg add it to 1 cup water and take 1/4 cup if you want 25mg; or 2 Tablespoons if you want 12.5mg; or 1 Tablespoon if you want 6.25mg. One teaspoon would be 2.08mg.....using 100mg Mino in 1 cup water. Another post said that the pharmacist said this would keep for 2 weeks in the refrigerator, if you are doing very low dose Mino. Shake well each use.

Meg's note: Tiny doses of minocycline are no longer recommended.

Last edited on Tue Dec 14th, 2004 05:24 by



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Renee_RN
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 Posted: Fri Sep 17th, 2004 02:22

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Hi Martha,

The pellets are a bit trickier than powder.  You could try something with an edge....... (& slight wall to hold them in.... and spread them out along the edge.

Anysize from a cookie sheet...... to an empty metal altoids box.  Something in between those sizes would be best.   I have a square brownie pan that works great..... about 8 x 8 in.....with about a half to 0.75 in high edge wall.

Spread them out along oneside in the crack as best you can...... and start dividing...... by 2...... then 4....... to your desired dosage.

Once you have 4 relatively equal doses....... scoop each division into a see thru gel cap.  Once inside...... you can compare the levels between the 4 standing on end.

If your mino has expired..... that may be an issue.  There was a thread on this and I believe both Meg and I responded to it.  Normally meds do not suddenly lose their effectiveness on the day of expiration.....and that is typically the only concern..... losing potency eventually.  BUT..... apparently there is some questionable toxicity/dangerous issue at least with other tetracyclines..... so if it is very far past the exp date.....would be best to investigate this further.

I remember looking into this a bit..... (and saw the potential problem w/ doxy/tetras) but I don't think I was able to confirm for certain if mino was an issue.... and decided not to use my old Rx just in case.

Last edited on Fri Sep 17th, 2004 02:27 by Renee_RN



____________________
Started MP 07.27.04
D Hydroxy 19.4 ng/mL (ref range 10-60)
D 1,25 Dihydroxy 34.2 pg/mL (ref range 25.1-66.1)
Dx: Chronic lyme, fibromyalgia,
Hx: CFIDS, IBD, IC. RSD. NMH, active CMV, EBV
Was bedridden 5 yrs, semi-functional past yr-2 w/ Zith. S
Renee_RN
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 Posted: Fri Sep 17th, 2004 04:14

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Martha,

Here is the link I was referring to re: the expired Mino/other cyclines

http://www.marshallprotocol.com/forum11/284.html



____________________
Started MP 07.27.04
D Hydroxy 19.4 ng/mL (ref range 10-60)
D 1,25 Dihydroxy 34.2 pg/mL (ref range 25.1-66.1)
Dx: Chronic lyme, fibromyalgia,
Hx: CFIDS, IBD, IC. RSD. NMH, active CMV, EBV
Was bedridden 5 yrs, semi-functional past yr-2 w/ Zith. S
spytfyre
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 Posted: Fri Sep 17th, 2004 04:27

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Quick question that I can't seem to find an answer to anywhere:  Any reason why you can't take the liquid form of minocycline?



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Orig diag: Giant Cell Vasculitis...60 mg Prednisone daily 4/1/04..1,25D 60/25D 8..weaning Pred7/08/04..now 7mg..Benecar 8/29/04 q6h..began pulsing 25mg Minocylcine 10/19/04 per my Dr & DrMarshall..now pulsing 200mg bd..Sups: Artemisinin 300mg bd-Reishi,As
Reenie
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 Posted: Fri Sep 17th, 2004 04:51

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Spytfire says, "Any reason why you can't take the liquid form of minocycline?"

The answer to that would be no reason why you couldn't use an elixir, however, as Lilly pointed out, when I called the pharmacist about adding mino to water, you need to use the liquid up within a short amount of time or it's pretty much useless, since it loses its potency.   

I would imagine when you get a liquid form of mino as with most abx, you are supposed to use it up in a short amount of time too. 

Maybe one way would be to get several divided doses of the elixir, before your pharmacist adds water to it, if he/she would dispense that way and allow you to add the water to each container when you were ready to use it.   

Last edited on Fri Sep 17th, 2004 04:55 by Reenie

spytfyre
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 Posted: Fri Sep 17th, 2004 05:26

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What I meant is, minocylcine can be prescribed in capsule form, tablet form, or liquid.  I would think the liquid form would be easier to measure.  Doc gave me a prescription for both in case there was some reason why Dr. Marshall would not recommend it in this form, but logic tells me it's the same thing - why not?.....best regards....Lynne G.



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Orig diag: Giant Cell Vasculitis...60 mg Prednisone daily 4/1/04..1,25D 60/25D 8..weaning Pred7/08/04..now 7mg..Benecar 8/29/04 q6h..began pulsing 25mg Minocylcine 10/19/04 per my Dr & DrMarshall..now pulsing 200mg bd..Sups: Artemisinin 300mg bd-Reishi,As
Paula Carnes
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 Posted: Fri Sep 17th, 2004 20:02

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You need to ask your pharmacist how long it will keep? You will be taking such low doses that the product might expire before you finish it, or worse you would be taking it and it won't be working.

Paula

Aussie Barb
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 Posted: Fri Sep 17th, 2004 22:15

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Lynne :)

do you mean as in children's syrup minocycline? I wonder if there is such a thing? can find out by asking at the pharmacist or perhaps online. :)

Best, Barb :cool:



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♥Barb♥: Dx Inflammation - Endocrine Imbalance 2003| Depression| 24+ years not Dx| MP Aug04-Aug2010| barbliv @ hotmail.com | ABC of MP| Barb's Story|
Margo
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 Posted: Tue Oct 26th, 2004 20:45

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Here is how I divide up a minocycline capsule in half (works for 50 mg and 75 mg capsules):

I get empty gel caps from the pharmacy or health food store. My pharmacist will order a box of No. 2 size capsules, 100 to a box. The cost is quite low. The No. 2 size works well, as it is just a bit larger than the minocycline capsules.

I open up several empty gel caps onto a clean plate. I then take the capsule of minocyline, open it up,and carefully set down the shorter end of the capsule.

Next, I empty most of the powder out of the larger side of the capsule into the larger side of an empty gel cap. I then close up the gel cap, and then the minocycline capsule. (This is easier if you have extra hands - maybe a family member can stand by.)

I label a clean, empty pill box, and put the divided capsules into it.

With this method, the capsules are pretty evenly, though not perfectly, divided.

Margo



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ava
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 Posted: Sat Oct 30th, 2004 19:37

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OK - my doctor has ordered the kids liquid form for me - he told this to the pharmacist Friday late afternoon, I didn't know til last night - won't be here 'til Monday or Tuesday.

I'm assuming liquid is OK after reading here,

and that the only possible problem is longevity?

Thanks, Ava



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Victoria: CFS since mono+ 37 yrs ago; endometriosis; osteopenia. high chol/trigl/cr protein; Ben 40mg Q8H 10/04/04| mino 11/15| 8/14/04: 25D=24 1,25D=45| Did over, 25D=7 now; finished phase 2; just moved to Mexico from Georgia US
Aussie Barb
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 Posted: Sat Oct 30th, 2004 20:14

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ava,

ask your pharmacist for all the information when you pick up your mino.

what we have heard so far is that it must be refrigerated,

and presumably shaken well before taking, and that it keeps for 2 weeks..

* If you gain any further information on that we would be pleased to hear it ...

thank you :) Barb....

see also minocin vs. minocycline



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♥Barb♥: Dx Inflammation - Endocrine Imbalance 2003| Depression| 24+ years not Dx| MP Aug04-Aug2010| barbliv @ hotmail.com | ABC of MP| Barb's Story|
LH1953
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 Posted: Thu Sep 15th, 2005 22:47

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The straws that have a bulb shape at one end that kids get with their slushy drinks make it so easy to split the antibiotic doses.  If you put the full dose at the end of one straw, then divide it with the second straw to equal parts, it makes it quick and easy. If you get the #0 capsules, they are wide. The straw is flexible and fits into the capsule, then just tap it in. The drinks are sold here at some Gas Stations, Costco or BJ's food stores.  So, the straws are free.  Hope this helps!



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Lyme, MCS, Interstitial Cystitis, Asthma, Reflux, Ulcerative Colitis, Osteopenia, Hypothyroid, EBV, 1,25D-48, MP 8/05, Proventil inhaler, Xopenex neb. Singulair, Probiotic, Diazepam, Fioricet, Zyrtec Ph3 7/06, NoIRs, limited outings D25 7 12/13

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