Now I have what may be an overly simplistic question, but here goes. If one were to take a sample from someone with Th1 prior to starting the MP, and then compare it to a sample post-MP, would this not give a strong proof of the validity of the Marshall pathogenesis? Further, considering the level of detail this process gives regarding the metabolic processes/pathways that (should) see change after treatment, would this be useful as proof of the efficacy of the MP specific to disease? In other words, is it possible to tease out the information about "disease", to show that it is reduced or eliminated by the MP?
Could this technology be the silver bullet to shoot into the heart of Koch's postulate to put it into the dustbin of history once and for all?
Yes, metagenomics will put Koch to bed within the next 5 years. The problem is that at the moment all the sequencing is being done assuming that the body is a sterile compartment. Yet note the 40% of DNA sequences which Merriman was unable to force into his human genome BFAST software. What were those DNA strands? Well, nobody has ever suggested that he try to match them against bacterial genomes. So he didn't. What is more, people like Dave Relman, who tried to ask difficult questions, have been shut out of grants to look at discoveries which might upset the status quo in clinical medicine. So we aren't there yet. But I think within 5 years
And hopefully the ARF will be one of the first... if our fundraising goes well,..
I can think of a million questions I would like to ask about the healing process, and, in time, genomic sequencing will help us get the answers.
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