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Metagenomics made easy
 Moderated by: Prof Trevor Marshall
 

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Prof Trevor Marshall
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Joined: Fri Jul 9th, 2004
Location: Thousand Oaks, California USA
Posts: 16040
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 Posted: Wed Aug 26th, 2009 12:55

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Yesterday I attended the San Diego Consortium on Systems Biology seminar at the Salk Institute.

http://sdcsb.ucsd.edu/index.php?page=workshop

There were one or two presentations there which will help us all understand Metagenomics and genome sequencing.

I have put this discussion in the MEMBERS ONLY area, to help those of you who have a need to understand the science in greater depth, but who cannot attend these meetings in-person.

Please join me over at:

http://www.marshallprotocol.com/view_topic.php?id=13429&forum_id=43

..Trevor..

Knochen
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Joined: Wed Feb 22nd, 2006
Location: USA
Posts: 369
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 Posted: Thu Aug 27th, 2009 09:48

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Trevor,

That was a very impressive talk!

Now I have what may be an overly simplistic question, but here goes.  If one were to take a sample from someone with Th1 prior to starting the MP, and then compare it to a sample post-MP, would this not give a strong proof of the validity of the Marshall pathogenesis?  Further, considering the level of detail this process gives regarding the metabolic processes/pathways that (should) see change after treatment, would this be useful as proof of the efficacy of the MP specific to disease? In other words, is it possible to tease out the information about "disease", to show that it is reduced or eliminated by the MP?

Could this technology be the silver bullet to shoot into the heart of Koch's postulate to put it into the dustbin of history once and for all?




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Prof Trevor Marshall
Foundation Staff


Joined: Fri Jul 9th, 2004
Location: Thousand Oaks, California USA
Posts: 16040
Status:  Offline
 Posted: Thu Aug 27th, 2009 10:31

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Yes, metagenomics will put Koch to bed within the next 5 years. The problem is that at the moment all the sequencing is being done assuming that the body is a sterile compartment. Yet note the 40% of DNA sequences which Merriman was unable to force into his human genome BFAST software. What were those DNA strands? Well, nobody has ever suggested that he try to match them against bacterial genomes. So he didn't. What is more, people like Dave Relman, who tried to ask difficult questions, have been shut out of grants to look at discoveries which might upset the status quo in clinical medicine. So we aren't there yet. But I think within 5 years :)

And hopefully the ARF will be one of the first... if our fundraising goes well,..
I can think of a million questions I would like to ask about the healing process, and, in time, genomic sequencing will help us get the answers.
 .


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