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The Antibodies Congress in Beijing, May 2009
 Moderated by: Prof Trevor Marshall Page:    1  2  3  Next Page Last Page  
 

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Prof Trevor Marshall
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 Posted: Wed May 27th, 2009 17:25

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Amy's presentation at the Antibodies conference in Beijing was very well received, with much of the audience staying 33 minutes into their lunch-hour to continue asking questions and engaging in the discussion.  The video of Amy's presentation is online at

http://vimeo.com/5106259

The presentation of Dr Xiangyang Huang, PhD, MD, of West China Hospital, Sichuan University, has also been placed online. It will give you some idea of the depth of molecular study being pursued there.

http://vimeo.com/5066949

A copy of Amy's abstract can be found here:
http://AutoimmunityResearch.org/abstracts/Proal_WCA_2009_abstract.pdf


I have now received written permission to republish the promotional video for West China Hospital, to help us all understand why the Foundation has put so many of its resources into helping WCH make the MP available in China. You can view the video at URL:

http://vimeo.com/2599727

This video can also be downloaded and played with VLC player, if your Internet connection is slow.
 

Last edited on Thu Jun 11th, 2009 08:28 by Prof Trevor Marshall

Deedee
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 Posted: Wed May 27th, 2009 19:59

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This is all very interesting and I enjoyed watching the video on the hospital.  From this statement from Amy's abstract, "West China Hospital is currently is collaborating to trial the VDR/antibiotic therapy in their autoimmune patients"----
 Does this mean the hospital will be conducting a clinical trial or observational study?  I heard on the video that they publish more on research articles than any other hospital in China.  Will their trial be published?



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06/08 Sarc in lymph nodes. Chronic high lipids. 2010 heath cat scan-zero plaque. 11/12 D8, 12/12 Normal CXR except scarred lymph node, normal PFTs 8/12 Off all MP meds. Metabolic Syndrome
Prof Trevor Marshall
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 Posted: Wed May 27th, 2009 23:44

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DeeDee, skeptics who demand more than an "observational" trial are never going to satisfied. Get used to it :):):)

WCH is the Cochrane collaborating center for China. Excellence in Evidence Based Medicine. I spoke with the head of the Clinical Trials Unit yesterday. It never entered his mind to insist that we have to do a "placebo, double blinded" trial. You see, there are experts in study design, and there are people who just pretend to be experts.

The trials at WCH will be initially set up to gather data, almost certainly using an "historical comparator" study design.

Initial studies will be to check the dosing of Benicar, measure the 25-D and 1,25-D levels in the population here, and get to grips with immunopathology. Only after the groundwork is in place will we move to efficacy studies :)
 

Russ
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 Posted: Thu May 28th, 2009 04:04

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Will the patients be taking antibiotics too or just Benicar?

By the way, congrats on all the progress you and the foundation are making.



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Deedee
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 Posted: Thu May 28th, 2009 05:26

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That had somewhat concerned me that some poor innocents would be fed placebos, but I am pleased to hear that this was not even considered.  The film talked a lot about their research, which lead me to wonder how the information they glean from the MP will be compiled and/or published. I can't wait to learn more about the "historical comparator" study design.  This is all very exciting.

I hope to visit that part of China someday.  My daughter-in-law is from Thailand and we have often talked about visiting China together.   The buildings in the video were beautiful.  I hope you have some time to enjoy the city and countryside while you are there.  Thank you very much for everything you are doing.   



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06/08 Sarc in lymph nodes. Chronic high lipids. 2010 heath cat scan-zero plaque. 11/12 D8, 12/12 Normal CXR except scarred lymph node, normal PFTs 8/12 Off all MP meds. Metabolic Syndrome
paulalbert
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 Posted: Thu May 28th, 2009 10:00

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To me, treatment efficacy means addressing MP patients' near universal IP reaction. How can a person explain IP if not through systematic and large-scale destruction of bacteria and human cells infected by bacteria?

Paul



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Diag CFS 6.03 / sympt since 9.02 / exercise, food intol, sleep prob / 1,25D: 16, 4.06; 1,25D:27, 25D:26 7.04; 1,25D:43, 25D:6 6.05; 1,25D:17, 25D:8 8.05; / MP: 7.04 / Ph. 3 / Bacteriality
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 Posted: Fri May 29th, 2009 09:38

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Seeing the department of psychiatry makes me wonder if the MP will be tried on mental health patients who have been admitted to the hospital (that is, if they have long-term patients).  It would be great to see people get well who need greater support because of the affect of IP on their emotions and thoughts due to the extent that Th1 has affected their mental health.  It seems to me that short-term hospitalization (whatever that means) would be a much better investment of money in all who are chronically ill than what we are currently doing.  Claire



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Prof Trevor Marshall
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 Posted: Sat May 30th, 2009 03:01

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In China they don't put Vit D in milkshakes or icecream. Surely a little bit woudn't hurt?





This young stranger walked up to us at the Panda Base, and wanted her picture taken with the crazy American:






Freddie Ash
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 Posted: Sat May 30th, 2009 04:13

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HI DR MARSHALL & AMY

This is Fred in WV. Just wanted to thank you both for all you have done in China.  Great pictures.  I am still pulling for us.

Remember, we are all in this together and I am pulling for us.

Your friend in Sarcoidosis

Freddie



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Prof Trevor Marshall
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 Posted: Sat May 30th, 2009 21:38

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This is at the DuJiang Yan water conservation (irrigation) project, which dates from the Ming Dynasty...


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 Posted: Mon Jun 1st, 2009 14:24

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Glad to see youre back on the road Trevor! :)

Br

Martin



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Prof Trevor Marshall
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 Posted: Tue Jun 2nd, 2009 08:37

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Another city, and another show...





This time an additional collaboration, with the Medical College of Luzhou:



After our lectures at West China Hospital Monday night, Amy and I were driven to Luzhou, a city of about 5 million, some 150 Km south of Chengdu. After overnighting at a hotel there, we were picked up for lunch, then whisked away to the Medical College for yet another 'Trevor Talk'...  This one was a little different, as we had Chinese translation following each one of my slides. I think the video will come out quite interesting... :)

Then whisked back to Chengdu (another 3-hour car ride), where Amy is trying to get some sleep before the chauffeur arrives at 6am to take her to the airport...

I have extended my trip a few extra days, and will fly home later this week...

I am not sure what was printed on that medal which Amy was given, but she is showing it proudly to the camera :):)
 

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 Posted: Tue Jun 2nd, 2009 13:41

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I couldn’t help but see the correlation between effective business models of industry and similar application to medical research and development. Both models become hindered when an excessive level of bureaucracy is layered on. It would also seem to me WCH has reflected china’s ideals, which is investing in the future, with what appears to be their efficiencies in biological research and experimentation. Dr, I would love to here a bit more of your personal observations on our differing cultures, with respect to their approach to this research.

“The US NIH has estimated that 90% of the cells in Homo sapiens are microbial and not human in origin”  

I would assume that this statement from Amy’s abstract might be common knowledge among researchers and scientists but for a laymen like me, it was just sobering. 

Tom



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paulalbert
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 Posted: Tue Jun 2nd, 2009 14:55

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The US NIH has estimated that 90% of the cells in Homo sapiens are microbial and not human in origin.
In Amy's and my experience, sharing this observation appears to be the most effective way to get people interested of the validity of the Marshall Pathogenesis.

By the way, this is NOT common knowledge among researchers. And even if it is, they don't know what to make of it.

Paul

Last edited on Tue Jun 2nd, 2009 14:56 by paulalbert



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Prof Trevor Marshall
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 Posted: Wed Jun 3rd, 2009 02:51

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After my presentation in Luzhou yesterday (it is pronounced loo-joe) Amy and I were taken to the 1573 wine-making company,where they have been making rice-based spirits the same way since the Ming Dynasty, hence the name '1573.'  Here are workers tending the fermenting rice piles, allegedly in the same way as in the Ming Dynasty:




Here is Amy, ceremonially  tasting some of the fresh 60% liqueur at the factory:





We both survived that experience, and we were taken to a dinner banquet, where rather a lot of the nice 1573 stuff was served.  This photo was supposed to show the vegetable delicately carved into  the shape of a peacock, but Amy zoomed it out a bit, and caught me in the photo, too:





Amy is winging her way home now with some bottles of 1573 in her luggage...


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 Posted: Wed Jun 3rd, 2009 04:17

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Thanks for the great photos.  It has me wishing I were there....What a great experience! 



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06/08 Sarc in lymph nodes. Chronic high lipids. 2010 heath cat scan-zero plaque. 11/12 D8, 12/12 Normal CXR except scarred lymph node, normal PFTs 8/12 Off all MP meds. Metabolic Syndrome
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 Posted: Wed Jun 3rd, 2009 06:53

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I hope everyone is noticing that Dr. M and Amy look wonderfully normal sitting outside without hats and  dark glasses. A gentle reminder that there is an endpoint if we all just persevere.:D
Mindy



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Prof Trevor Marshall
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 Posted: Sat Jun 6th, 2009 05:51

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I returned home from China yesterday. Amy is home too.

There will be a formal Press Release in a few days, after we finish working out all the details, but I figured you all might like to know what happened :) Here is a photo summarizing the most important point:




Yesterday I signed an "Agreement on collaboration of the California Autoimmunity Research Foundation and the Dept of Rheumatology at the West China Hospital/West China Medical on the Clinical study of the Marshall Protocol therapy in Chinese patients"

Our agreement calls for in-vivo, ex-vivo and in-vitro studies to explore all levels of the science, as well as the therapy. The clinical studies will be large, with hundreds of patients, and last for 2 years, along with longer-term follow-up. The clinical studies will be controlled against a DMARD/NSAID control patient group.

The Foundation will soon start a fund-raising drive to help pay for the cost of running the trials.

I want to thank Amy, Liz, Paul, Chris and Cathy Benediktsson, and all (of you) who have worked so turn this opportunity into reality. I expect to make a more detailed announcement later this week :):)

I have a video of a presentation from Assoc. Prof. Huong showing the quality of Sichuan University's in-vitro work which I will try and put online in a few days, along with Amy's presentation at the Antibodies conference, and my presentation at Luzhou (the presentation which has the concurrent Chinese translation).
 

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 Posted: Sat Jun 6th, 2009 06:09

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This is enormous news!  Congratulations!  I am just so excited I hardly know what to say!!!


 



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06/08 Sarc in lymph nodes. Chronic high lipids. 2010 heath cat scan-zero plaque. 11/12 D8, 12/12 Normal CXR except scarred lymph node, normal PFTs 8/12 Off all MP meds. Metabolic Syndrome
Ute
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 Posted: Sat Jun 6th, 2009 06:27

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Very impressive!

My best wishes to the whole poject!



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