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A 'Baldness gene' identified
 Moderated by: Prof Trevor Marshall
 

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Prof Trevor Marshall
Foundation Staff


Joined: Fri Jul 9th, 2004
Location: Thousand Oaks, California USA
Posts: 15970
Status:  Offline
 Posted: Fri Apr 16th, 2010 02:52

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http://www.medicalnewstoday.com/articles/185645.php

Interesting that the VDR normally down-regulates this APCDD1 gene (Wang et al shows a negative 'score'). Clearly we still have a lot to learn.

I note that Hans Clevers' presentation identified lgr4/lgr5/lgr6 as markers for stem cell activity in the mouse hair follicle, Wang showed lgr4 is strongly expressed by the VDR...
 


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