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Immunostimulation in the Era of the Metagenome
 Moderated by: Prof Trevor Marshall
 

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Prof Trevor Marshall
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 Posted: Mon Jan 31st, 2011 06:00

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This morning Cellular and Molecular Immunology published our paper: "Immunostimulation in the Era of the Metagenome."

http://www.nature.com/cmi/journal/vaop/ncurrent/abs/cmi201077a.html

My sincere thanks to the many who helped Amy write this wonderful paper.

Its particular significance is that it describes for the first time the phenomena of immunopathology, and describes clinical events which many physicians may regard as adverse events, showing that they were an integral component of the healing process.

A full-text preprint is online at:
http://autoimmunityresearch.org/preprints/Proal2010CellularMolecularImmunologyPreprint.pdf
 
...Trevor..

JohnMcC
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 Posted: Mon Jan 31st, 2011 06:27

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Dr M
The pre-print download is only 1 page - will the rest become available?

Many Thanks
John

Worked after a few attempts - windows...grr

Last edited on Mon Jan 31st, 2011 07:20 by JohnMcC



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terrylmcc
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 Posted: Mon Jan 31st, 2011 06:56

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GOOD WORK, AND CONGRATULATIONS TO ALL THAT CONTRIBUTED.

JOHN, All 20 pages are available on this end. I would give the link another try.
Best --Terry



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scooker48
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 Posted: Mon Jan 31st, 2011 09:48

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This is a turning point for everyone at Autoimmunity Research Foundation and the MP.

Keep up the good work.

Sherry



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Deedee
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 Posted: Mon Jan 31st, 2011 16:35

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"
Cases like A.C.’s strongly suggest that the sooner an
immunostimulative treatment is started, the less
immunopathology a patient may have to manage, and
the quicker the potential recovery."

This would be good info to reference on the MPKB, since from time to time someone will state he is and he will wait to wait to see if the disease will "go away."



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ChrisMavo
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 Posted: Wed Feb 2nd, 2011 01:50

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Bravo!!  Excellent paper!!  I congratulate all of those who contributed to it.

Let us hope that with the publication of this paper and the recent chapter in the book, that the Marshall Protocol will begin to become a mainstream treatment option for more people suffering chronic disease worldwide!



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scooker48
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 Posted: Wed Feb 2nd, 2011 07:24

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I finished reading the paper last night, and it is the most lucid explanation yet.

I will be sending it out to friends...

Sherry



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D25, Total: 12 measured 11/3/15 Started MP=01/04/05 Diagnosis: Sarc 12/04; "cat scratch disease" or necrotizing graunulomas 10/88; Raynaud's (diagnosed 1980?)
Pipistrelle
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 Posted: Thu Feb 3rd, 2011 02:04

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Many thanks to everyone who worked so hard on this.  It is so clear to read, I too will be sending it off to key people.

Congratulations!

Morag



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Ames
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 Posted: Sat Feb 5th, 2011 07:51

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Hi guys,

For those of you that have commented, I'm so glad you like the paper!  I'm happy that you think it's fairly accessible!

I also appreciate your kind words about the book chapter for the JCVI textbook.  It was nice to finally have a forum in which to really pull the Pathogenesis together.

I hope everyone is herxing tolerably and take care!

Amy



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Pipistrelle
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 Posted: Sat Feb 5th, 2011 13:37

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Pity we don't have a thanks button, would have pressed it oh, several hundred times... thanks again for all the team's dedication and diligence.

Morag



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Guss Wilkinson
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 Posted: Sat Feb 5th, 2011 18:51

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Fantastic paper guys.

I just had a health check - my first since getting off the MP at the new year (after 7-years).

I feel really good and my health check indicated that I am in good shape all round except for a couple of the blood test results.

This paper explains the out of range values for kidney and liver functions, which suggest that I may be a little premature in stopping the MP.

But it doesn't explain the elevated  calcium results (which is at 3.00 mmol/L). This result has my GP really concerned as it could indicate malignancy.

Any comments?

Cheers

Guss



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Dx Sarc May 2002 Stage 2. Estimate Sarc since 1987. Lungs, Joints, Kidneys & Liver.(Started MP: Oct 2003 - stopped permanently June 2012) The MP doesn't seem to have worked for me.
Prof Trevor Marshall
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 Posted: Sat Feb 5th, 2011 21:04

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Correlation of calcium with malignancy does not imply causation.
You are correct, you did stop Olmesartan too soon, let it do its job, which includes a number of cancer-protective pathways. See, for example, the two I talk about here:

http://www.youtube.com/watch?v=y8AfUg3aJVk

Great to hear things are going well, Guss :)

..Trevor..
 

k
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 Posted: Sat Feb 5th, 2011 23:52

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Yep, definitely accessible Amy.



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wirion
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 Posted: Thu Feb 24th, 2011 01:48

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Hi!
I'm not sure whether this is the right place to ask for this, but I would like to show the published version of Amy's paper to my doctor (rather than the preprint). I know it shouldn't make a difference, but doctors are people and might take the published version more seriously.

In any case, massive thanks to Amy and her coauthors for their fantastic work! :)

François



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paulalbert
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 Posted: Thu Feb 24th, 2011 10:58

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Hi François,

I feel the same way. The original seems to carry more weight. So, here it is for now:
http://dl.dropbox.com/u/2014679/Proal2011MolecularClinicalFinal.pdf

I will take it down in 24 hours or so.

Any chance you would care to contribute to a French translation of the MP?

This is a Google Translate version of this page, and we need a French speaker to clean up this rough automated translation.
http://mpkb.org/home/translations/french

Best,
Paul



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Jigsaw
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 Posted: Fri Feb 25th, 2011 00:33

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Tahnks for a great paper. I am though a bit confused by the rather non-sequitor mention of epidermal growth factor receptor (EGFR) a the bottom of p8, followed by discussion of eGFR (estimated Glomerular Filtration Rate) and kidney function.



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Prof Trevor Marshall
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 Posted: Fri Feb 25th, 2011 02:19

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Sigh... Typos do slip through now and then...

paulalbert
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 Posted: Fri Feb 25th, 2011 05:52

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Yes, typos do "slip through now and then" but this was not a typo.

This change was introduced by editorial for the pre-print. Then when we were reviewing this suggested change, we told editorial, "This change would be bad. Please use 'estimated glomerular filtration rate'."

I don't understand why they would ask for us to review their changes if they're just going to ignore them.

Paul



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Prof Trevor Marshall
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 Posted: Fri Feb 25th, 2011 06:06

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paulalbert wrote: I don't understand why they would ask for us to review their changes if they're just going to ignore them.
I never argue with an editor :) They don't listen, and then they don't publish you again :) Through 20 years of editors at Byte.com I never found one which deviated from that methodology :) 'Time and motion' drives everything in the print business :)

wirion
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 Posted: Fri Feb 25th, 2011 16:22

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Hi Paul,
and thanks for the paper.

Yes I'll give editing the French translation of the MP a shot. I should mention that despite my name I'm not a native French speaker. I had a brief look at the Google translated document and did find some errors. On Sunday I'll go on holiday for 3 weeks, but tomorrow I'll have some time to look at it in more depth.



____________________
CFS EBV Ph1Apr07 Modph2Jun07 Ph3Sep07 abx brk Nov07-Jan08 Jul08-Sep08 July10-? 25D<5(Jul08) 25D=5(Nov09) 25D=5(Nov10) 25D=3(Mar12) 25D=6(Oct12) 25D=5(Feb14) 25D<8.0(Jan15).

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