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The Marshall Protocol Study Site > PROF. MARSHALL'S PERSPECTIVE > Prof. Marshall's Perspective > International Congress on Autoimmunity 2012, Granada


International Congress on Autoimmunity 2012, Granada
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Prof Trevor Marshall
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 Posted: Fri May 18th, 2012 03:32

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The 2012 International Congress on Autoimmunity, in Granada, Spain, saw presentations from myself (one plenary, one shorter) and from Inge Lindseth. I also chaired two sessions.

Inge's video presentation can be found at http://www.youtube.com/watch?v=2IMdAV6SIMU

while the PDF transcript is at: http://autoimmunityresearch.org/transcripts/Auto2012_IngeLindseth.pdf

There were 7 other presentations on CFS/ME at the Congress.

It is notable that among this top-notch audience of researchers and rheumatologists there is now general acceptance that CFS/ME is an immunological disease, most probably autoimmune in nature, which can be detected using antibody assays. IMO, that is a stunning step forward for the CFS/ME community.

----------

The video of my plenary session is now online at http://www.youtube.com/watch?v=g6sH7NTXkjw

As I start to wind down from the frenzy of activity which characterizes these big conferences (there were 2300 delegates this year) I will post some other thoughts, and some of my memorable photos.
 
 
 

Last edited on Sat May 19th, 2012 01:11 by Prof Trevor Marshall

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 Posted: Fri May 18th, 2012 07:04

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Inge's presentation is really well done and easy to understand. :)

I am going to forward this to both my PCP and infectious disease specialist in hope that it gives them a glimmer of understanding of what we're doing here.

Looking forward to seeing more from this Congress in Spain soon! :D



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 Posted: Fri May 18th, 2012 10:19

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Thank you for your efforts and ideas and well done lecture!

Best for all of you!

Titta



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 Posted: Fri May 18th, 2012 11:23

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The thing I'm enjoying most about the presentations and reports from conferences is the steady movement of the medical industry in the direction of accepting many of the preliminary concepts required for confidence in the Marshall Pathogenesis, and of course, Protocol.

Inge drew a clear line of evidence and begged the correct scientific approach: "Please test our hypothesis" with a big friendly welcome.

Inge's report was very refreshing: straight forward and very easy to compare 10 years of standard of care dominated by illness, inability to work and death to that of a larger cohort on two different continents that in 2-3 years showed all responding to treatment exactly as the science predicts (whether they opted to continue treatment or not) and a whopping 1/3 that stayed the course for a while went back to work full time, with the note that not everyone even started the MP at the same time but all are included.

Nice black box discussion that leaves the black box to just be what it is, but helps divert focus to positioning and competition per the nuclear receptor.

Thank you Inge!--Janet



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 Posted: Sat May 19th, 2012 01:05

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Bravo Inge!  An excellent and clear presentation that is easy to understand! 

Thanks!

Good health,
Chris



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Prof Trevor Marshall
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 Posted: Sat May 19th, 2012 01:08

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The video of my plenary session is now online at http://www.youtube.com/watch?v=g6sH7NTXkjw

..Trevor..
 

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 Posted: Sat May 19th, 2012 01:48

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Both of the presentations are very well done, thank you Dr. Marshall.:)



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 Posted: Sat May 19th, 2012 06:15

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Thanks for posting them, well done.

Are the conferences bigger than they used to be? I noticed lots of applause!

Deb



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wrotek
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 Posted: Sat May 19th, 2012 06:29

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Molecular mimicry is amazing (18 minute of a video).
Does E. Coli produce angiotensin ?

Can receptor that looks exactly the same as homo sapiens, be responsible for totally different signal pathways ?  Murine VDR is, is not it ?

Last edited on Sat May 19th, 2012 06:32 by wrotek



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Prof Trevor Marshall
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 Posted: Sat May 19th, 2012 06:35

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There were 2300 at this year's congress, easily the biggest yet. But there were 6 parallel session rooms (focusing on different topics). Inge was talking in a small room, but it was packed to the gills with people, all of whom were enthusiastic about "infection in autoimmunity". I gave my plenary in the second biggest hall, as it was on the last day, Sunday, and many had left early so they could be at work on Monday morning. But there were hundreds left :) And all the most important people :) And yes, both our presentations were received very well.
 
I also chaired the Vitamin D session, which took place after my keynote (Sunday afternoon). It, too, filled the smaller parallel session room, but nothing interesting or new turned up there :)
 

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 Posted: Sat May 19th, 2012 06:42

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Can't believe you lost your whole presentation at one point, you got it back quickly!



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I just know that something good is going to happen
And I don't know when - Kate Bush
Aplastic anemia Apr/10, PRCA Jan/09, Agranulocytosis 1991
25D = 25 1,25D = 58 Aug 18/09|25D<4.8 Mar/10|10.8 Nov/12
Sep '09 q8h Nov '09 q6h
mvanwink5
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 Posted: Sat May 19th, 2012 06:44

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Thanks Dr. Marshall and Inge Lindseth,
I just wish I could get my friends to watch. One thing that struck me was a chart Dr. Marshall showed before in a video conference, displaying a "heat" diagram of the microbiome. The diagram implied that the majority of our microbes were common to our food source, implying that our bugs are what we eat. Although I now avoid salads, I still eat fruit which for me is always uncooked.

I always found the case study of the MS patient who started out incontinent and in a wheel chair and recovered, compelling, although I am unsure of the final outcome. It would be of interest to me what the age was of that person and where he is today if that is available.

I also always find it compelling to tie the new laboratory technology to the advent of the microscope and the medical knowledge revolution that resulted when that last happened. So commensurately this is truly phase 2 of that revolution.

Best regards as always,
Mike

Last edited on Sat May 19th, 2012 06:46 by mvanwink5



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Prof Trevor Marshall
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 Posted: Sat May 19th, 2012 06:49

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Deb,
It was a Congress laptop computer, remotely controlled by a VNC network by a technician in a central control room. But they left me a mouse and a keyboard, and that's all I needed :)

What was weird was that the slide on the laptop screen, and the slide on the projector, were different throughout the presentation. Like I said, weird, but no real problem...
 
I used to try and use my own laptop, but at the bigger conferences it wastes a minute or two while the projector cables are changed. So these days I am happy to use a conference machine.
 

Prof Trevor Marshall
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 Posted: Sat May 19th, 2012 06:56

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Mike,
Last time I spoke to Greg about that MS patient (before I went to the FDA last year) she was still stable/improving, although she had started to focus more on enjoying life, rather than push her therapy so hard :)
 
As for that food heat-map slide, the slide gives a citation to Eric Alm's paper in Nature -- where you can see all the details about his study. I met Eric in Seattle, where he gave a presentation about his lab's work... The 'DNA in air' slide came from Craig Venter's presentation in Seattle. There are two other similar slides, detailing New York air (inside and outside) and the air on the end of the Scripps' pier in San Diego. I decided to use a minimum this time, as I was racing to fit all the key points into my allotted half-hour (as you saw)...

I am glad you liked the "Computer Microscope" idea. It is tough to figure out how to communicate the importance, or the complexity, of that early in-silico work. Even today, I rarely see Gromacs being asked to do anything really useful.  PhRMA are all using very crude technologies, by comparison. As far as I know, I am the only person who has used Modeller to model bacterial proteins and study Molecular Mimicry...
 
 
 

Last edited on Sat May 19th, 2012 07:06 by Prof Trevor Marshall

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 Posted: Sat May 19th, 2012 06:57

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I'd say it's a big bonus to be able to troubleshoot stuff like that! I never would have guessed from your presentation that anything was off between the laptop and the big screen either, so well done.

Deb



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I just know that something good is going to happen
And I don't know when - Kate Bush
Aplastic anemia Apr/10, PRCA Jan/09, Agranulocytosis 1991
25D = 25 1,25D = 58 Aug 18/09|25D<4.8 Mar/10|10.8 Nov/12
Sep '09 q8h Nov '09 q6h
mvanwink5
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 Posted: Sat May 19th, 2012 07:00

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wrotek wrote:
Molecular mimicry is amazing (18 minute of a video).
Does E. Coli produce angiotensin?

Can receptor that looks exactly the same as homo sapiens, be responsible for totally different signal pathways?  Murine VDR is, is not it?
This to me is also a salient topic and quickly mentioned by Dr.Marshall was the drug acting as a ligand for bacterial proteins. That has to gum up the little buggers, so what are the implications there? Perhaps it is good for us in our battle. Do you have an idea of what that is doing, good/bad, no way to tell?
Best regards,
Mike



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Prof Trevor Marshall
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 Posted: Sat May 19th, 2012 07:08

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No way to tell about the drug effects, Mike. Nor whether the receptor's primary role is to upset the host, or promote the metabolism of the bacterium.
 

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 Posted: Sat May 19th, 2012 08:26

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Dr. Marshall,

Do you got the impression may be by the bilateral discussions before and after your presentation that there is more acceptance for the protocol and the basics.
 



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Prof Trevor Marshall
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 Posted: Sat May 19th, 2012 08:54

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Gerard, a single presentation does not change concepts and perceptions. But I think both Inge and I saw an eagerness to listen to what we had to say, and I had several (important) people come up to me afterwards saying something like "I get it now" :)

..Trevor..
 

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 Posted: Sat May 19th, 2012 09:32

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Repetition, from different people, and time.... Now, is this a good time to ask for an FDA update?:cool:
Best regards
Mike



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