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wrotek member

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Posted: Mon Jul 27th, 2015 12:13 |
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I have absolutely no idea it was 20-30 years ago
Still it is amazing doctors see cases like that and they don't think why osteoporosis is not getting better and they do the same over and over again to treat this condition
Last edited on Mon Jul 27th, 2015 18:08 by wrotek
____________________ Borreliosis(4 strains),Bartonella IgG only, reflux,headache TMJD ,chronic pain,chronic fatigue,depression 125D36 Ph1Sep05 Ph2Oct06 Ph3Apr07 in low lux NoIRs 25D<7 Oct06
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hartley member
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Posted: Mon Aug 3rd, 2015 21:26 |
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I had to revisit this thread to bolster my thinking after reading this today on the BBC website...
http://www.bbc.co.uk/news/health-33757929
____________________ MPJan2011nobreaks / Lyme'05 / C.Pneumonia'05 / Asthma / Joint Pain / Ocular Hypertension / Anxiety / 25DSept'12=3.04 ng/ml / 25DMay'14=5.12ng/ml
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Prof Trevor Marshall Foundation Staff

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Posted: Mon Aug 3rd, 2015 21:45 |
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Thanks, Hartley, I will use that in my keynote in Toronto - on the hazards of Biomarker design...
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Prof Trevor Marshall Foundation Staff

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Posted: Tue Aug 4th, 2015 02:46 |
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Another paper - Vit-D supplements same value as placebo
"High-dose cholecalciferol therapy increased calcium absorption, but the effect was small and did not translate into beneficial effects on bone mineral density, muscle function, muscle mass, or falls. We found no data to support experts’ recommendations to maintain serum 25(OH)D levels of 30 ng/mL or higher in postmenopausal women. Instead, we found that low- and high-dose cholecalciferol were equivalent to placebo in their effects on bone and muscle outcomes in this cohort of postmenopausal women with 25(OH)D levels less than 30 ng/mL"
http://archinte.jamanetwork.com/article.aspx?articleid=2422066
http://www.reuters.com/article/2015/08/03/us-health-menopause-bones-idUSKCN0Q81TV20150803
Even though they were under 30ng/ml (12 ng/ml) NO BENEFIT 
..Trevor..
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leroybrown ...

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Posted: Tue Aug 4th, 2015 13:53 |
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If everyone is deficient in vit D, how come you never hear of anyone who actually has rickets?
____________________ I just know that something good is going to happen
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Aplastic anemia Apr/10, PRCA Jan/09, Agranulocytosis 1991
25D = 25 1,25D = 58 Aug 18/09|25D<4.8 Mar/10|10.8 Nov/12
Sep '09 q8h Nov '09 q6h
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wrotek member

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Posted: Tue Aug 4th, 2015 14:29 |
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I asked the same question to mine doctor. Rickets only occurs in young developing bones. The disease of developed bones is osteoporosis
p.s. i used to have rickets and they gave me vitamin D... I still have some uneven skull, mother used to put mine head on one side one time and the other side the other time, because it was so soft like eggshell , she was forming it LOL
Last edited on Tue Aug 4th, 2015 14:31 by wrotek
____________________ Borreliosis(4 strains),Bartonella IgG only, reflux,headache TMJD ,chronic pain,chronic fatigue,depression 125D36 Ph1Sep05 Ph2Oct06 Ph3Apr07 in low lux NoIRs 25D<7 Oct06
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madhouse member
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Posted: Fri Aug 7th, 2015 19:22 |
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I see this thread started several years ago but apparently nothing has changed. I work in the medical profession and Doc's still push vit D like candy. In fact all my chronic inflammatory or "autoimmune" patients are on mega doses of it. Medicare in the US requires us to council fall patients on the importance of vit D supplementation to prevent broken bones. I will not do it!
Vit D is alive and well folks! It's going to take more than a few studies to stop it.
____________________ RA 2 Years. IBS 15 years
Started MP 6/15/09 Now off all Meds and doing well.
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Prof Trevor Marshall Foundation Staff

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Posted: Fri Aug 7th, 2015 19:42 |
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Well, at least there are a series of studies now showing you are correct. However, the papers all use big words, way beyond the capabilities of Medicare decision-makers 
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Claudia member

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Posted: Mon Aug 24th, 2015 11:32 |
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On Australian ABC radio today:
http://mpegmedia.abc.net.au/rn/podcast/2015/08/hrt_20150824_1730.mp3
Here's the web page reference (in case the above podcast audio doesn't work)
http://www.abc.net.au/radionational/programs/healthreport/calcium-vitamin-d-supplements-necessary/6720616
Cheers!
ClaudiaLast edited on Mon Aug 24th, 2015 11:53 by Claudia
____________________ MP Phase1 23Mar_06; Phase2 July 10_06; Phase3 Nov 4_06. Dx Thyroiditis (Thyroxine); arthritis; glaucoma; CFS (1988-92);Kidney & bladder probs., Osteoporosis Dx 2015, Burning Mouth Syndrome! 2016. Feb06 1,25D=43.3; Aug07 1,25D=27.5; Feb06 25D=44; Mar08
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mvanwink5 Support Team

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Posted: Mon Aug 24th, 2015 12:01 |
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Thanks, Claudia.
So, researchers are now saying, basically, 'tough luck,' and miss the chronic disease forest for the tree leaves.
____________________ Lyme joints, RF shielding needed, MP start 8/10; 25D <4ng/ml 8/20; vegetarian; olmesartan 240mg/d, Zinc Picolinate, Ivermectin, Fenbendazole,Nitazoxanide, Hydroxychloroquine My Progress: http://tinyurl.com/z2stwo8
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Claudia member

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Posted: Mon Aug 24th, 2015 12:11 |
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yeah, basically they are saying "we are puzzled" but at least they admit the past studies were wrong AND biased.
We have to hope they go on to ask the obvious questions about WHY they got those results! We live in hope..
____________________ MP Phase1 23Mar_06; Phase2 July 10_06; Phase3 Nov 4_06. Dx Thyroiditis (Thyroxine); arthritis; glaucoma; CFS (1988-92);Kidney & bladder probs., Osteoporosis Dx 2015, Burning Mouth Syndrome! 2016. Feb06 1,25D=43.3; Aug07 1,25D=27.5; Feb06 25D=44; Mar08
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Damselfly member

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Posted: Mon Sep 21st, 2015 06:16 |
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As a relative newcomer I am trying to catch up on protocol-related reading and research linked on the study site and anywhere else I can find it. I noted that the paper reporting a study finding that vitamin D does not improve calcium absorption, referenced in Prof. Marshall’s 10/31/2013 post in this thread is no longer behind a paywall and can be accessed in full by clicking on the same link provided in 2013. http://onlinelibrary.wiley.com/doi/10.1002/jbmr.2121/abstract and then selecting PDF. There is so much new (to me) information – including studies such as this that turn decades of thinking upside down. My sense is that Prof. Marshall has put a puzzle together while much of the scientific community is getting more puzzled by the pieces.
Last edited on Mon Sep 21st, 2015 06:32 by Damselfly
____________________ MP Aug ’15 (no breaks)/Acute anterior iritis ’15/eye inflammation, both, serial; hypothyroid diag. 2006 (9 yrs)/25D result 7.4 ng/mL 10/4/2015/(Note – on MP 2010-2011 1.5 yrs. for other immune problems)
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Claudia member

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Posted: Sat Jan 9th, 2016 01:57 |
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And another recent study - this one shows that "Vitamin D" supplementation not only does not help, it actually increases falls and fractures.
http://archinte.jamanetwork.com/article.aspx?articleid=2478893
____________________ MP Phase1 23Mar_06; Phase2 July 10_06; Phase3 Nov 4_06. Dx Thyroiditis (Thyroxine); arthritis; glaucoma; CFS (1988-92);Kidney & bladder probs., Osteoporosis Dx 2015, Burning Mouth Syndrome! 2016. Feb06 1,25D=43.3; Aug07 1,25D=27.5; Feb06 25D=44; Mar08
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Claudia member

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Posted: Tue Sep 13th, 2016 05:00 |
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What do we know about this lot?
http://www.sunarc.org/about.htm
____________________ MP Phase1 23Mar_06; Phase2 July 10_06; Phase3 Nov 4_06. Dx Thyroiditis (Thyroxine); arthritis; glaucoma; CFS (1988-92);Kidney & bladder probs., Osteoporosis Dx 2015, Burning Mouth Syndrome! 2016. Feb06 1,25D=43.3; Aug07 1,25D=27.5; Feb06 25D=44; Mar08
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Joyful Foundation Staff

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Posted: Tue Sep 13th, 2016 05:30 |
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They are truly in the dark. 
http://www.pharmacynews.com.au/news/latest-news/doctors-slam-calcium-and-vitamin-d-conflict-of-int
Same cast of characters. Also, see Benefactors page:Benefactors Information
SUNARC is incorporated under California law. The federal 501(c)3 form has been submitted, and SUNARC is being operated in accordance with the guidelines for nonprofit public interest corporations.
Disclosure
SUNARC receives funding from Bio-Tech Pharmacal, Inc. (Fayetteville, AR) and the Vitamin D Council (San Luis Obispo, CA).
Last edited on Tue Sep 13th, 2016 05:47 by Joyful
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Claudia member

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Posted: Tue Sep 13th, 2016 06:36 |
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Hi Joyful, thanks. I went ahead and looked them up myself and found all their conflicts of interest, plus one of their listed benefactors doesn't seem to exist.
(Someone had quoted them to me in a FB post, and I wanted to refute their stuff.)
____________________ MP Phase1 23Mar_06; Phase2 July 10_06; Phase3 Nov 4_06. Dx Thyroiditis (Thyroxine); arthritis; glaucoma; CFS (1988-92);Kidney & bladder probs., Osteoporosis Dx 2015, Burning Mouth Syndrome! 2016. Feb06 1,25D=43.3; Aug07 1,25D=27.5; Feb06 25D=44; Mar08
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Joyful Foundation Staff

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Posted: Tue Sep 13th, 2016 18:07 |
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As the body of quality research grows,
the "More is better!" club keeps losing members ...U-shaped relationship between vitamin D levels and long-term outcome in large cohort of survivors of acute myocardial infarction.
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Claudia member

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Posted: Thu Sep 15th, 2016 13:33 |
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A friend of mine recently told me that redheads make more vitamin D than other folks. Apart from the pale skin allowing more sun in, they are saying that the actual genetic mutation responsible for red hair (mutated MC1R gene) also causes increased production of vitamin D.
Is there any substance to this belief?
Thanks for the input!
Claudia (definitely a "carrier" of this gene, having spawned a redhead!)
____________________ MP Phase1 23Mar_06; Phase2 July 10_06; Phase3 Nov 4_06. Dx Thyroiditis (Thyroxine); arthritis; glaucoma; CFS (1988-92);Kidney & bladder probs., Osteoporosis Dx 2015, Burning Mouth Syndrome! 2016. Feb06 1,25D=43.3; Aug07 1,25D=27.5; Feb06 25D=44; Mar08
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Prof Trevor Marshall Foundation Staff

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Posted: Sat Sep 17th, 2016 19:35 |
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Very little (only a few percent) of the Vit-D in the blood is generated in the skin. Each cell produces the Vit-D it needs -- without any sunlight.
Direct sunlight causes the skin to start a damage response, and the (healthy) body then generates more Vit-D internally. But nobody has been able to measure an generation of Vit-D in the skin itself - of either mice or men. This is an old-wives' tale.
I would suspect the redhead gene thing is also lacking in science.
..Trevor..
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Claudia member

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Posted: Mon Sep 19th, 2016 08:47 |
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OK, I understand about those things, but what do you know about the mutated MC1R gene that was mentioned? I didn't know anything about it, mutated or otherwise, until a friend brought the subject up. I've had a look online and found several interesting articles suggesting there is certainly something - or several things - going on with redheads apart from hair colour. This includes their being twice as likely to have Parkinson's and a link to inflammatory response. Here is one quote:
"The melanocortin 1 receptor is also active in cells other than melanocytes, including cells involved in the body's immune and inflammatory responses. The receptor's function in these cells is unknown."
- https://ghr.nlm.nih.gov/gene/MC1R
This article seems to touch on both the VDR and MC1R, but I don't understand the science.
http://www.neurology.org/content/62/12/2323.short
This article, although not scholarly, was interesting:
http://www.medicaldaily.com/8-ways-having-red-hair-affects-persons-health-pain-sex-348198Last edited on Mon Sep 19th, 2016 08:48 by Claudia
____________________ MP Phase1 23Mar_06; Phase2 July 10_06; Phase3 Nov 4_06. Dx Thyroiditis (Thyroxine); arthritis; glaucoma; CFS (1988-92);Kidney & bladder probs., Osteoporosis Dx 2015, Burning Mouth Syndrome! 2016. Feb06 1,25D=43.3; Aug07 1,25D=27.5; Feb06 25D=44; Mar08
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