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Two presentations from ACA 2013 Hong Kong
 Moderated by: Prof Trevor Marshall
 

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Prof Trevor Marshall
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Joined: Fri Jul 9th, 2004
Location: Thousand Oaks, California USA
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 Posted: Thu Dec 5th, 2013 11:13

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At the Autoimmunity Congress Asia n Hong Kong I delivered two presentations. One was my plenary - an updated version of how the microbiome causes chronic disease, and one was a short 15 minute presentation on "Autoantibodies - are they the cause, or result, of Autoimmune Disease?"

The two presentations are now on YouTube at:

http://www.youtube.com/watch?v=pMU9d67ShoQ

http://www.youtube.com/watch?v=sOQYRxRn-sU

Notable in the plenary is my increasing ability to talk sensibly about the importance of our in-silico discoveries, building on the 2013 Nobel prize for Chemistry. But you will find quite a bit of new stuff in this presentation, I think.

The autoantibodies presentation was pretty controversial. But I feel it is time to talk about this topic, however taboo it might be in the eyes of some Rheumatolgists...

..Trevor..
 

wrotek
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 Posted: Sat Feb 8th, 2014 04:15

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"If antibodies are the cause of disease, You should get rid of them and You would get rid of disease" . http://youtu.be/sOQYRxRn-sU?t=9m40s

Are these memory B cells invaded by bacteria ?



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wrotek
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 Posted: Sun Feb 9th, 2014 04:40

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Also, what do researchers think sustains auto-antibody production, if not persistent infection ?



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Prof Trevor Marshall
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Joined: Fri Jul 9th, 2004
Location: Thousand Oaks, California USA
Posts: 15811
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 Posted: Sun Feb 9th, 2014 06:25

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"Are these memory B cells invaded by bacteria" -- Yes. See the Wirostko study

You know, there are a lot of strange, wild, theories about what triggers autoantibodies. None of them make sense. Most pervasive are the "trigger" hypotheses, where exposure to an environmental agent triggered the formation of B-cells in the first place, and the body has not been able to clear the resulting auto-antigens. I have heard top-level physicians noting that that if you live near an airport (and jet fumes) you will have a very high risk of autoimmunity, sarcoidosis is associated with being near pine forests, and so on. The level of understanding of the immune system is not great, nor is there any real will to find out the truth. Disease is seen as being already sufficiently complex to understand, there is no push to make it more so.
 

wrotek
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 Posted: Sun Feb 9th, 2014 06:34

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I recently encountered a medical doctor who used herbs to decrease his ANA antibodies in his LUPUS . He now sells those herbs anonymously referring to the part of Your work Dr Marshall about L-forms(that herbs kill L forms apparently).

So ANA could drop relatively fast even on herbs...
But whether he is healthy, that is another story.

Last edited on Sun Feb 9th, 2014 06:38 by wrotek



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