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The Marshall Protocol Study Site > PROF. MARSHALL'S PERSPECTIVE > Prof. Marshall's Perspective > Chlorogenic Acid in Coffee is powerful Immune modulator


Chlorogenic Acid in Coffee is powerful Immune modulator
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wrotek
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 Posted: Wed Mar 14th, 2012 11:18

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From second link that Keithw gave.

“Of the 52% rigidly on the diet [with­out night­shades], 94% reported com­plete or sub­stan­tial relief of arthri­tis…”– Jour­nal of Neu­ro­log­i­cal and Ortho­pe­dic Med­ical Surgery

Other interesting experience with nightshades.
http://www.youtube.com/watch?v=WQ5Nau-p0-o

Person from them above movie, had 80% decrease in arthritic pain, but still he did not quit smoking :D

[Could it be that adverse effects attributed to nightshades, might actually have an explanation in chlorogenic acid actions ?

BTW coffee (cga ?) makes me laxative extremely :) , and wikipedia lists chlorogenic acid containing prunes as laxative.
http://en.wikipedia.org/wiki/Chlorogenic_acid

Tea is much less intense laxative.


http://www.youtube.com/watch?v=LDnFVDGb1wE

Last edited on Wed Mar 14th, 2012 16:00 by wrotek



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Cynthia S
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 Posted: Wed Mar 14th, 2012 20:00

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I always thought it was the oil in coffee, as I never got the same reaction from instant.  Cynthia



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Seth
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 Posted: Thu Mar 15th, 2012 05:49

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Cynthia,
Thats interesting. I wonder if the extra processing (freeze-drying,etc) removes the chlorogenic acid from instant coffee.



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Sarcoidosis |dx-Sep'09|Ph1-Mar'10|Ph2-Jul'10|Ph3-Jan'11|O-only-Aug'11|bone marrow biopsy|splenomegaly,lungs,joint/muscle/stomach pain,sweats,fatigue,headaches,mood swings,brain fog |25D<10ng/ml-Dec'10-June'11| Splenectomy June 2016. DEATH TO THE BUGS!
Kas
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 Posted: Thu Mar 15th, 2012 06:34

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I drink the Nescafe instant coffee and have no reaction whatsoever. Just one cup every now and then - have cut back from daily, but see no difference yet. lLiver enzymes were better on coffee, but kidneys seem better off it on one test. I will wait and see what the next one shows.



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wrotek
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 Posted: Fri Mar 16th, 2012 05:19

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Solanecae contain interesting steroid like compounds that come from cholesterol http://www.plantphysiol.org/content/131/4/1792/F1.expansion.html
like

solanine http://en.wikipedia.org/wiki/Solanine

chaconine http://en.wikipedia.org/wiki/Chaconine

tomatine http://en.wikipedia.org/wiki/Tomatine




Potato glycoalkaloids and adverse effects in humans: an ascending dose study.
http://www.ncbi.nlm.nih.gov/pubmed/15649828

There can be as much as 200mg/kg of Tocal Glycoalkaloids in potatoes.

In the following paper, on second page, are compared structures of alkaloids found in solanecae plants http://www.ib-pan.krakow.pl/pubs-pdf/Wiadomosci%20Botaniczne/1973/17_a23-32.pdf

Last edited on Fri Mar 16th, 2012 05:54 by wrotek



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wrotek
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 Posted: Fri Mar 16th, 2012 07:28

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Here is an interesting book http://unilibrium.net/healthfiles/NightshadefreePainFree!e-BookbyMichaelFowler.pdf

about nightshades. I like especially similarity between
cardiac glycosides like this - oleandrin and nightshade toxins.

We know that patients with immunopathology can experience quite dagerous heart palpitations...
Apparently this toxins can constribute to heart beating faster.

Last edited on Fri Mar 16th, 2012 07:30 by wrotek



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wrotek
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 Posted: Sat Mar 17th, 2012 09:21

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some testimonials http://www.30bananasaday.com/forum/topics/nightshade-testimonials

Hello,

I have been sick for so long that I had given up hope of ever feeling better. I have been diagnosed with trigger fingers, jumper's knee, tennis
elbow and I don't shoot guns, jump hurdles or play tennis. My C Reactive Protein was so high the doctor's thought I had ALS. I have been
checked for RA, Lupus, MTG on and on.... I was practically bed ridden. I could only walk a few feet without pain and my joints throbbed
24/7. Last month I started seeing an acupuncturist for the pain, he suggested I do a cleansing and stop eating nightshades. I had heard of
nightshades but did not realize they were actually killing me...slowly. I have thyroid problems, borderline diabetes, joint pain and
inflammation, vitamin D deficiency. I was researching nightshades when I stumbled across this website. All my conditions can be traced back
to nightshades. I eat tomatoes like apples and potatoes are a staple in my diet. NO MORE! I stopped eating nightshades immediately and
Thank God I did! I have been pain free for two weeks now. I can work in my garden and I can walk long distances without stopping.
Thank you for all that you do in researching this condition. Without this information, I would still be suffering needlessly.
Carolyn

Last edited on Sat Mar 17th, 2012 09:22 by wrotek



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keithw
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 Posted: Sat Mar 17th, 2012 14:01

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Personally, I consider both nightshades and gluten as like pouring petrol on the fire.

If you leave them out of your diet they can't hurt you and things have to settle at a lower level even for MPers.

There is a lot of truth in the old adage that a balanced diet is healthy and drinking several cups of coffee every day and living on potatoes and bread have to change the overall chemistry of the body away from the norm.

It's just common sense, if you are sick try and find the cause rather than compensating for it, removing the irritants from your diet will lower your overall IP and make MP so much easier and that means lower drug costs as the need for palliation also drops.

:dude:



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keithw
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 Posted: Sun Mar 18th, 2012 19:13

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I have pretty much finished reading the book "Nightshade free pain free" as posted by Wrotec above.
The first part is mostly taken from the poisoners handbook and not much use to us but the latter parts have some realistic information taken from works by many researchers including Wang who we base some of our own work on so I am forced to take it seriously.

For those that follow this thread it seems likely that they could significantly ease their progress by following some of the dietary guidelines as mentioned in this book and I would like to see some of the info copied into MPKB as a resource for patients that can be quickly linked to rather than posting a URL to someone elses web page which may have contrary and confusing info.

Not sure if I can do it as I don't have editing access to MPKB but maybe I can help put something together.

:dude:



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WeanPred May09 no breaks SLE, CNS vasculitis, avascular necrosis, arthritis both shoulders Ph1Aug09 Ph2Nov09 Ph3Feb10 25D35(May09)18(Mar10)16.7(Jul10)13.6(Jan11)13.2 (Oct 11)14.8(Aug 12) around 35(Jul14)due to weight loss!
jlunn247
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 Posted: Mon Mar 19th, 2012 02:06

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC523841/
with out the mp i had developed a food avoidance obsession.
for few months before the mp untill i was just eating turkey and navy beans:shock: I know i can have "some" pizza just not everyday:)

is oatmeal a low gluten food or not?
i can eat 2-3 servings it never bothers me
is it ok for the mp?

Last edited on Mon Mar 19th, 2012 02:33 by jlunn247



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wrotek
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 Posted: Mon Mar 19th, 2012 06:33

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Personally, I consider both nightshades and gluten as like pouring petrol on the fire.

But this can be also due to high carbohydrate content of potatoes or bread



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Grateful Survivor
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 Posted: Mon Mar 19th, 2012 16:28

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Jjunn,

I'm not really savvy about gluten, but my impression is that oatmeal is gluten-free.  Hopefully someone will correct me if I'm wrong.

Oatmeal (old fashioned, slow-cooked; not instant) has a much lower glycemic index that most other grains especially wheat.  I eat oatmeal, with a lttle fruit and a big spoonful of almonds, for breakfast every day.  I cook a 3-day batch every 3 days, refrigerate it, and reheat  it in the microwave the other 2 mornings.

All best,
Dody



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wrotek
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 Posted: Wed Mar 21st, 2012 06:42

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There are a lot of products that contain a potato flour, which is used as a thickening agent.

It is not so easy avoiding nightshades, if one was inclined to do that.

from wikipedia
Potato starch and potato starch derivatives are used in many recipes, for example in noodles, wine gums, cocktail nuts, potato chips, hot dog sausages, bakery cream and instant soups and sauces, in gluten-free recipes[3] in kosher foods for Passover[4] and in Asian cuisine.[5] In pastry, e.g. sponge cake, it is used to keep the cake moist and give a soft texture. It is also occasionally used in the preparation of pre-packed grated cheese, to reduce sweating and binding. Helmipuuro is a porridge made from monodisperse grains of potato starch and milk.

Last edited on Wed Mar 21st, 2012 07:59 by wrotek



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wrotek
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 Posted: Wed Mar 21st, 2012 13:48

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Solanine and Chaconine

http://www.inchem.org/documents/jecfa/jecmono/v30je19.htm

Interesting summary



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Reef
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 Posted: Thu Mar 22nd, 2012 05:22

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is oatmeal a low gluten food or not?
i can eat 2-3 servings it never bothers me
is it ok for the mp?


You have to buy gluten free oatmeal/oats in order to be certain that it is gluten free. Oatmeal is easily cross contaminated with gluten as it is usually grown in close proximity to wheat. Regular oatmeal is probably a low gluten food, but not gluten free.



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 Posted: Thu Mar 22nd, 2012 09:56

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Hi wrotek,

I do not eat potato's for the last 25 years after a test on food alergies potato proved to be wrong. It gives me a headage and makes me tired. On the MP I also developed a in-toloreance for the other nightshades. Tomato and chili peppers and parika and eggplant. Potato starch is so purified that it never bothered me. If the poison is out the strach is harmless ( to me).

Now there is the difficult chalange where is the poison? I did not find any other alternative than slimply try. The labels on food do not mention less than 1 % or so fractions in the food, which makes it impossible to be sure, unless you cook from cratch.

best regards erik ( roelof)



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wrotek
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 Posted: Sat Mar 24th, 2012 09:21

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Potato glycoalkaloids and adverse effects in humans: an ascending dose study.

http://www.ncbi.nlm.nih.gov/pubmed/15649828

Abstract
Glycoalkaloids in potatoes may induce gastro-intestinal and systemic effects, by cell membrane disruption and acetylcholinesterase inhibition, respectively. The present single dose study was designed to evaluate the toxicity and pharmacokinetics of orally administered potato glycoalkaloids (alpha-chaconine and alpha-solanine). It is the first published human volunteer study were pharmacokinetic data were obtained for more than 24 h post-dose. Subjects (2-3 per treatment) received one of the following six treatments: (1-3) solutions with total glycoalkaloid (TGA) doses of 0.30, 0.50 or 0.70 mg/kg body weight (BW), or (4-6) mashed potatoes with TGA doses of 0.95, 1.10 or 1.25 mg/kg BW. The mashed potatoes had a TGA concentration of nearly 200 mg/kg fresh weight (the presently recognised upper limit of safety). None of these treatments induced acute systemic effects. One subject who received the highest dose of TGA (1.25 mg/kg BW) became nauseous and started vomiting about 4 h post-dose, possibly due to local glycoalkaloid toxicity (although the dosis is lower than generally reported in the literature to cause gastro-intestinal disturbances). Most relevant, the clearance of glycoalkaloids usually takes more than 24 h, which implicates that the toxicants may accumulate in case of daily consumption.



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wrotek
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 Posted: Sat Mar 24th, 2012 14:42

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http://worldofcaffeine.com/the-great-duality-coffee-tea/

The Great Duality: Coffee & Tea
The Disparate Cultures of Coffee and Tea


I think comparison reflects different effects two beverages have on people personalities :)

Last edited on Sat Mar 24th, 2012 14:46 by wrotek



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wrotek
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 Posted: Thu Mar 29th, 2012 08:07

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Do Nightshades contain Vitamin D 3 ?
http://noarthritis.com/research.htm

Osteoarthritis appears to be a result of long-term consumption and/or use of the Solanaceae which contain naturally the active metabolite, vitamin D3, which in excess causes crippling and early disability (as seen in livestock). Rigid omission of Solanaceae, with other minor diet adjustments, has resulted in positive to marked improvement in arthritis and general health.

:?

I found this reading Mr Fowler Nightshade book

Last edited on Thu Mar 29th, 2012 08:14 by wrotek



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scooker48
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 Posted: Thu Mar 29th, 2012 08:19

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Wow!

This is fascinating.

Thanks,

Sherry



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