'Days of Molecular Medicine' 2007 - Prof. Marshall's Perspective - PROF. MARSHALL'S PERSPECTIVE

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'Days of Molecular Medicine' 2007

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Ruth Goold
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Joined:	Thu Oct 19th, 2006
Location:	Nanaimo, British Columbia Canada
Posts:	236
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Posted: Sat Aug 11th, 2007 13:41

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Trevor,
Do you know which class(es) of AMPs are most effectove against the intracellular Th1 pathogens when the VDR is operating properly?
Ruth

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Prof Trevor Marshall
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Joined:	Fri Jul 9th, 2004
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Posted: Sat Aug 11th, 2007 15:24

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Ruth,
No, nobody really knows very much about how they work. In particular, some AMPs seem to be able to adapt conformation depending on the organism which is present. "Micro-RNA" loops were being discussed as a possible adaptive mechanism during the conference at Salk on January. I haven't had time to look into this in more detail yet.

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