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'Days of Molecular Medicine' 2007
 Moderated by: Prof Trevor Marshall Page:  First Page Previous Page  1  2   
 

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Ruth Goold
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Joined: Thu Oct 19th, 2006
Location: Nanaimo, British Columbia Canada
Posts: 236
Status:  Offline
 Posted: Sat Aug 11th, 2007 14:41

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Trevor,
Do you know which class(es) of AMPs are most effectove against the intracellular Th1 pathogens when the VDR is operating properly?
Ruth



____________________
03/02/07 Ph 1 MP; 2001: Pulmonary sarc; 01/04/07: 125 D=110pmol/L(45.8 pg/ml)| 25D=20.8 ng/ml: 04/07 19.2: 07/07 11?: 09/07 16.5: 11/07 <10.0: 01/08 <10.0: 05/08 10 ng/ml. Ca. Elocom (ears). diphenhydramine 25 mg. Adidas EE glasses outside. NoIRs
Prof Trevor Marshall
Foundation Staff


Joined: Fri Jul 9th, 2004
Location: Thousand Oaks, California USA
Posts: 16176
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 Posted: Sat Aug 11th, 2007 16:24

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Ruth,
No, nobody really knows very much about how they work. In particular, some AMPs seem to be able to adapt conformation depending on the organism which is present. "Micro-RNA" loops were being discussed as a possible adaptive mechanism during the conference at Salk on January. I haven't had time to look into this in more detail yet.

 


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