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Workshop on Chlamydial Infection 2009
 Moderated by: Prof Trevor Marshall Page:  First Page Previous Page  1  2  3  4   
 

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Prof Trevor Marshall
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 Posted: Thu Apr 30th, 2009 09:57

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I have proof-read the Science presentation and the MP presentation+MP questions. Is anybody working on transcribing the Q&A session for the Science presentation?
 

paulalbert
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 Posted: Thu Apr 30th, 2009 10:04

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I think this is wide open. Whoever does it, I'll check the spelling and put it up for you.

Paul



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Joyful
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 Posted: Thu Apr 30th, 2009 20:40

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Oh! Sorry.

I transcribed the first question and the HIV video slide last night but didn't post them until just now... the questions are really hard to hear, but I'll finish up here with the last one shortly.


Edited to add:

The questions are transcribed as best as I could pick out the meaning between the background noise and interesting Prague accent.

Your answers, Dr. Marshall, were far easier to make out as I have become quite familiar with your special dialect of Southern (California) Australian! ;)


Last edited on Fri May 1st, 2009 02:23 by Joyful



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wrotek
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 Posted: Fri May 1st, 2009 04:28

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I like the presentation very much.

Especially enjoyed that HIV moves from one cell to another without entering space between cells- the movie in the end of presentation is great. I wonder, would making cells separated somehow , less agglutinated helped to slow down infection progression and improve treatment ?

Is there a good paper to read about how HIV uses VDR machinery for it's benefits ? Would love to read something about it. 

Last edited on Fri May 1st, 2009 04:28 by wrotek



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paulalbert
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 Posted: Fri May 1st, 2009 04:31

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Have a look at the KB's work in progress article on HIV/AIDS.



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wrotek
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 Posted: Fri May 1st, 2009 04:52

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thx



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Prof Trevor Marshall
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 Posted: Fri May 1st, 2009 05:23

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Thanks Joyful, Thanks Ron, Paul, and everyone. I have proof-read the Q&A session and have sent the transcripts and slides to Janet so that she can create the all-important hard-copy transcript to print for those Doctors who never touch a web browser :):)

Thanks, everybody. These two presentations, despite my bumbling around with words, will serve to let people know how far along we are in understanding the importance of the Th1 metagenomic microbiota to mankind :):)

Later this month Amy will be giving a presentation on "Antibodies and Infection in the Era of the Metagenome" at the  Intl Congress of Antibodies in Beijing. I will be accompanying her at the conference, I will be filming her talk, and will also traveling to West China Hospital to complete our planning there. Amy's presentation is something for us all to look forward to :):)
 

Joyful
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 Posted: Sun May 3rd, 2009 00:39

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Dr. Marshall,

I thought your presentations were very good.

Due to our international audience, having you say the same thing a couple of different ways should be helpful to overcome the language barriers. That's how I perceived your manner of speech. (Not as bumbling.) But I know how awful it can feel to review your own presentations after the fact... always room for improvement.

However, from this somewhat 'critical' reviewer, I came away with a great respect for your ability to pull complex concepts together to "tell the story" and saw you as being very effective at bringing those concepts within reach of your audience. :cool:



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eClaire
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 Posted: Sun May 3rd, 2009 10:14

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I will ditto Joyful in that.  I think your ability to story tale the science and the MP is getting better and better, and I think this is an essential skill for catching the imagination of the intended audience (even doctors and researchers whom one would think this might not be necessary)!! 

Claire



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Rico
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 Posted: Thu May 7th, 2009 17:04

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Trevor, I've only listened to the Prague videos for the first time, this evening. I wonder how well your Infectious Disease/Metagenome presentation was taken? I mean, you said in so many words at a Clamydial Conference that they are wasting their time focusing on Clamydia co-infections rather than with intraphagocytic pathogens. Curious...

Very interesting, indeed.

Rico

Last edited on Thu May 7th, 2009 17:05 by Rico



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Prof Trevor Marshall
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 Posted: Thu May 7th, 2009 18:51

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At least part of the audience were suffering from Chlamydial infection, and looking for answers. I also felt that the physicians were looking for answers too. Remember they also invited Chuck Stratton (the Stratton Protocol) (Prof Sririam actually made the trip).

Why would they invite the MP and the SP if they weren't looking for answers?

I will be watching for signs of follow-up over the next few months :)
 

jrfoutin
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 Posted: Sat May 23rd, 2009 21:10

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OK, the presentations are ready to look over and I sent them to Dr Marshall.



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Prof Trevor Marshall
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 Posted: Sun May 24th, 2009 05:48

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Janet's transcripts are suitable for printing and giving to Doc. You can find them at:

http://AutoimmunityResearch.org/prague_2009/science.pdf

http://AutoimmunityResearch.org/prague_2009/MP.pdf
 
Thanks for doing these transcripts, Janet, Ron and all the others who helped :):)

eClaire
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 Posted: Sun May 24th, 2009 10:35

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   JANET!!!



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Limburg
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 Posted: Sun May 24th, 2009 12:14

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Beautiful, Janet! :D

Last edited on Sun May 24th, 2009 12:15 by Limburg



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 Posted: Tue May 26th, 2009 08:54

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This is so exciting.  These two presentations (thank you Janet for the great transcriptions) are the best summaries I've seen yet.  I will be printing both for docs and for seriously interested friends.   --Dody 



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 Posted: Tue May 26th, 2009 12:41

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Beautiful job everyone. I love the clinical aspects that are being addressed in the conferences this year. I can finally see the MP as a working protocol for mainstream medicine. I am working up packets to give not only Caitie's doc but to other doctors we see throughout our journey. Well done!  :D
Mindy



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Frans
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 Posted: Sat Jun 6th, 2009 11:42

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Trevor,

You mention the study where M. Tubercolosis downregulated the VDR 3.3 fold.

I was wondering if we know which mechanism they utilise to do so ? Is it capnine ?

Best, Frans



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Prof Trevor Marshall
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 Posted: Sat Jun 6th, 2009 18:16

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Frans, the result is described in this study, although the mechanism is still unknown:

"Synergistic action of vitamin D and retinoic acid restricts invasion of macrophages by pathogenic mycobacteria"
http://www.ncbi.nlm.nih.gov/pubmed/18327422

I might add that the VDR seems to have some similar functions to PXR, FXR and the other newly discovered nuclear receptors, and I would be surprised if VDR down-regulation is the only effect present.

Capnine is a ligand, while the actual production of VDR itself is what was found to be down-regulated in the earlier M.tb study I cited in Prague. They used a micro-array to make their measurements. It is generally believed that the VDR itself is primarily transcribed by the newly-discovered Estrogen-receptor-beta
 


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