"QseC plays a role in invasion of epithelial cells and intramacrophage survival."
____________________ CFS symptoms | 25D9(Mar09) | 25D14(Jun09) | 25D6 (Sept11) Ph1Apr09 | Ph2Aug09 | Ph3Jun10 | drop back to Ph1Nov10 | Olmesartan only q6h since early 2011
"Using a high-throughput screen, we identified a small molecule, LED209, that inhibits the binding of signals to QseC, preventing its autophosphorylation and consequently inhibiting QseC-mediated activation of virulence gene expression."
____________________ CFS symptoms | 25D9(Mar09) | 25D14(Jun09) | 25D6 (Sept11) Ph1Apr09 | Ph2Aug09 | Ph3Jun10 | drop back to Ph1Nov10 | Olmesartan only q6h since early 2011