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Rico
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Posted: Sun May 22nd, 2011 11:30 |
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Interestingly, before Olmesartan was approved for sale in Canada, we used to buy it from the U.S. and it smelled sort of buttery. The Olmetec tablets we buy now in Canada does not have this odor.
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No diagnosis/some symptoms (more than I knew); wife with Sarc on MP; Olm 40mg q4-6h | 25D=22 (May 2014) | 25D=27 (Nov 2014)
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luxman
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Posted: Fri May 27th, 2011 07:07 |
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All the Olmetec (Sankyo's European olmesartan brand) I've been taking for over two years now in Luxembourg smelt like butter with no exception. Has it all been rancid?
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MP Mar'09 (break since Oct'13) | Undiagnosed | Asymptomatic, previously 24/7 dizziness, GERD, GI complaints, weakness, sciatica | Last 25D13.8 (Jan10)
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leroybrown
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Posted: Fri May 27th, 2011 07:43 |
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Rico - all my olmetec smells like butter.
Deb
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I just know that something good is going to happen
And I don't know when - Kate Bush
Aplastic anemia Apr/10, PRCA Jan/09, Agranulocytosis 1991
25D = 25 1,25D = 58 Aug 18/09|25D<4.8 Mar/10|10.8 Nov/12
Sep '09 q8h Nov '09 q6h
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cbay
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Posted: Fri May 27th, 2011 07:47 |
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Luxman,
I don't know about it being rancid. I have mixed Olmecip and Benicar (which all smelt buttery) and feel no difference between the two. We are talking about half a day taking Olmecip then switching. Or even taking one for a few days then the other. They both palliate and cause IP the same way for me.
Correcting my Olmesartan to say BenicarLast edited on Fri May 27th, 2011 09:46 by cbay
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MP July'10 | OCD`94, GERD`03, IBS`04, ADHD`05, Depression`07, Anxiety `10 | 125D45 June10 | 25D25 Sept14 | My Progress
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Cynthia S
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Posted: Fri May 27th, 2011 09:14 |
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| Are you people telling us about the olmesartan, or how good your sense of smell is? LOL, Cynthia
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MP start 10/08,break 1/16 - 9/16, Spondylitis'97,early Diverticulosis'98,early AMD'08,Calcium anomaly'95,TypeII Diabetes(?)'02,Degenerative hip disease'12, 25D=10.8 May'18 (preMP 125D/25D=47/43) https://marshallprotocol.com/forum30/13911-2.html
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cbay
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Posted: Fri May 27th, 2011 09:48 |
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That is funny to say 
I have times where I can smell scents that others have no idea. Sometimes I wonder if I am imagining them.
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MP July'10 | OCD`94, GERD`03, IBS`04, ADHD`05, Depression`07, Anxiety `10 | 125D45 June10 | 25D25 Sept14 | My Progress
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PGA Terry
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Posted: Sun May 29th, 2011 22:31 |
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Funny Cynthia!..... I have about a years supply of Olmesartan (Olmecip in the blister packs) and was wondering how is the best way to store these meds so they don't go rancid. I think Dr. Marshall mentioned keeping Olmesartan in the refrigerator for long storage but I'm not sure if I am remembering that accurately. If anyone has successfully stored Olmesarten for long periods I would appreciate you sharing.
Thanks.....Terry
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Ank spondylitis/RA - Ph1Aug07 Ph2Jan08 Ph3Mar09, Tylenol, Vits for malabsorption: cal-mag boron melatonin, vit b,c,e, multi-mineral, 4/09-125D=20, 7/13-25D= 4
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Jigsaw
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Posted: Mon May 30th, 2011 05:16 |
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I have had olmesartan medoxomil tablets (Olmetec) in blister packs at -4 celsius (in our household freezer) for at least 8 months without noticing any evidence of deterioration, either in the form of an odour or of loss of effectiveness. I have also kept powdered olmesartan medoxomil in capsules in tightly sealed plastic jars at -4 celsius for about three years without evidence of deterioration.
I have just tried one of them now, dispensed over 4 years ago by a compounding pharmacist in Melbourne. Again no smell or taste. I think the pharmacist got his supply from India and they worked well for me for the first 6 months on the MP. Then Olmetec was registered for supply on the PBS ( Pharmaceutical Benefits Scheme) and we could get it more cheaply and the tablets were easier to take. I had bought a big stock of the capsules at the end of 2006 and early in 2007. With a lot of them unused I switched back to them over the last half of 2009, early 2010 and they were fine. I have kept one jar as a souvenir or maybe for use if I need powdered olmesartan.
Last edited on Mon May 30th, 2011 05:17 by Jigsaw
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MP Feb,'07. Arthritis'78. CKD'07. Last 25D=7ng/ml Feb'13.
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Prof Trevor Marshall
Foundation Staff
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Posted: Mon May 30th, 2011 05:25 |
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Jigsaw, FYI, we just did an HPLC test run on a year-old jar of Pure Olmesartan bulk powder from our manufacturer in China, and it was still approx 99.7% pure (by HPLC)(omitting the 0.5% water). The jars have been kept at room temperature (avg 22 C)
The bulk Olmesartan Medoxomil will be less stable, the compound is far more polar, but I suspect it should be fine at lower temperatures. I don't expect capsules to interact with either the PO or OM in any way which would degrade its shelf-life. That said, most pharmaceutical grade empty-capsules are only certified for a 2-year shelf life.
It is my understanding that the Indian suppliers repackage bulk OM product from Chinese manufacturers. China is shipping tonnes of OM, and it has to be going somewhere (probably to Sankyo in Germany, too...).
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Markt9452
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Posted: Mon May 30th, 2011 05:44 |
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Mark,
I tend to disagree with you about the butter smell indicating the Benicar is rancid. I just got my 540 pills 2 days ago and I know that the pharmacist opened all foil sealed bottles to count them into the container I get them in. I opened the bottle when I got home and they smelled like butter. They ALWAYS do.
I can't believe that all the Benicar I have received for 7 yrs now is rancid.
Don't mean to discount your theory, Mark.
HANG IN THERE, WE WILL MAKE IT!!!!BARNEY
Not my theory Barney - I asked a PhD in Biochem. about the buttery smell.
The question I asked was
Q - "Can you identify a chemical compound by it's buttery odor?"
A - "It's rancid".
Q - "are you sure?"
A - "Yes - It is rancid - period "
My generic blister-pack Olmetec has no buttery odor.Last edited on Mon May 30th, 2011 05:45 by Markt9452
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MP Feb08 (no breaks) light sensitivity, fatigue, confusion, muscle twitching, memory loss, dyslexia, skin lesions, sore feet, electrical sensations, vertigo, tinnitus, 125D20 D25<10 2008
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Joyful
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Posted: Mon May 30th, 2011 21:20 |
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Mark, no disrespect to the highly educated pharm guy, but the butter odor has been documented from the beginning as some kind of undeclared impurity in the Sankyo brand Benicar tablets. They smell that way from day one.
Smells just like buttered popcorn to me. Very odd.
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Markt9452
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Posted: Tue May 31st, 2011 06:46 |
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| Seems to work fine with or without the buttery goodness...
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MP Feb08 (no breaks) light sensitivity, fatigue, confusion, muscle twitching, memory loss, dyslexia, skin lesions, sore feet, electrical sensations, vertigo, tinnitus, 125D20 D25<10 2008
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jrfoutin
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Posted: Tue May 31st, 2011 08:35 |
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This is indeed a great time in history, I hope we can get that PO going soon. Very, very good thing!
Best to all--Janet
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Sarcoidosis 125D61, MP10/05 ModP2 12/05 Ph2 6/06 Ph3 10/06, NoIRs limited outings covered, 2/08 25D6.2, 10/08 25D6.9
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cathys2007
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Posted: Tue May 31st, 2011 09:00 |
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| Another MP'er once told me that benicar's buttery smell seems to dissipate as you progress through MP. I guess the more you heal the less it smells like buttered popcorn. There may be something to it because I hardly notice the smell any more.....or maybe I have become accustomed it.
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MP 7/7/08 Dx Sarcoid-determined by lymph node, skin, stomach biopsies/neurosarcoid, FMS, IBS, Chronic Fatigue, brain fog, Primary Parahyperthyroidism, MTHFR, migraines, TMJ, Narcolepsy, Osteopenia, Gerd, Raynauds, Thoracic outlet, poss Lyme/D125=48(Mar07)
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lionel forbes
member
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Posted: Tue Jul 5th, 2011 21:08 |
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| May I respectfully suggest that the smell is caused by the th1 disease process itself .I used to get a sewer smell every time I ate lunch,until I realised that it was due to the combination of rice biscuit and peanut butter. I now consider myself "cured" after 5 1/2 years and for some time now that sewer smell has gone, so p has the buttery smell of Olmesartan.regards,
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sarcoidosis phase 1 jan 2006,phase 2 march 2006, phase 3 september 2006.Currently taking only olmesartan 40mg every 6 hours.
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jlunn247
inactive member
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Posted: Sun Jul 24th, 2011 12:29 |
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drying off after long shower i used to smell mildew on many a fresh towels till i realised it was my own body.
the bleach in the water changed my body odor or scewed up my olfactory senses.
and i cant stand fresh bread smell i got to toast it before it smells normal.Last edited on Sun Jul 24th, 2011 12:32 by jlunn247
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Living in the land of the lost. JUST OLMECIP 5 x a day.Sarcoidosis Dx.
Bone disintegration,lungs,joint/muscle/stomach pain, diarrhea,incontinence. Weakness on my left side sweats,fatigue,neuropathy,headaches,mood swings,cognitive diss.
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findinganswers
member
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Posted: Tue Aug 2nd, 2011 21:11 |
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| My doctor gives me Benicar samples from time to time and although I have been on the MP for 4 years now, they still always still smell buttery to me, whereas my Olmecip tablets do not have this smell to them.
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Diabetes type I hypothyroid IBS ADD GAD 125D37 25D12 Ph1Sept07 Ph2Jun08 ModPh2Nov08 25D8.5(June08) 25D<4(April2010) 25D5.5(Oct2010) 25D4(Jan2011) 25D7.4(Oct2011) 25D4(Feb2012) Levoxyl Lantus Humalog Cal/Mag Supp. qod Julbo Dolgan sunglasses light exp
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