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 Moderated by: Prof Trevor Marshall  
Prof Trevor Marshall
Foundation Staff

Joined: Fri Jul 9th, 2004
Location: Thousand Oaks, California USA
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There has just been some data on the canine version of the Cathelicidin anti-microbial peptides made available:

"Canine cathelicidin (K9CATH): Gene cloning, expression, and biochemical activity of a novel pro-myeloid antimicrobial peptide" PMID: 17462733

This joins the earlier paper:

"Molecular cloning and characterization of three beta-defensins from canine testes"  PMID: 15845463
The data here cannot be directly applied to Homo sapiens, but does give a pretty good indication of what these peptides can do...

What I found surprising was the wide anti-microbial spectrum, and especially the activity of the beta-Defensins against Candida...


Joined: Thu Dec 30th, 2004
Location: Wroclaw, Poland
Posts: 2979
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Is their mechanism of action bactericidal ? Do they kill  CWD too ?

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