|Moderated by: Prof Trevor Marshall|
Prof Trevor Marshall
|There has just been some data on the canine version of the Cathelicidin anti-microbial peptides made available:
"Canine cathelicidin (K9CATH): Gene cloning, expression, and biochemical activity of a novel pro-myeloid antimicrobial peptide"
http://tinyurl.com/yuuwen PMID: 17462733
This joins the earlier paper:
"Molecular cloning and characterization of three beta-defensins from canine testes"
http://tinyurl.com/yp6aox PMID: 15845463
The data here cannot be directly applied to Homo sapiens, but does give a pretty good indication of what these peptides can do...
What I found surprising was the wide anti-microbial spectrum, and especially the activity of the beta-Defensins against Candida...
|Is their mechanism of action bactericidal ? Do they kill CWD too ?
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